J Korean Ophthalmol Soc > Volume 52(12); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(12):1541-1544.
DOI: https://doi.org/10.3341/jkos.2011.52.12.1541    Published online December 15, 2011.
A Case of Cataract after Long-Term Use of Clonazepam in a Young Patient.
Byung Ju Choo, Young Suk Kang, Tai Jin Kim, Jung Hyun Park
1Department of Ophthalmology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. hyuny@medimail.co.kr
2Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
젊은 환자에서 장기간의 클로나제팜 복용 후 발생한 백내장 1예
주병주1⋅강용석2⋅김태진1⋅박정현1
Department of Ophthalmology, Seoul Paik Hospital, Inje University College of Medicine1, Seoul, Korea Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine2, Seoul, Korea
Abstract
PURPOSE
To report a case of cataract after long-term use of clonazepam in a young patient, with a similar appearance to cataract induced by other psychotropic agents. CASE SUMMARY: A 37-year-old woman complained of a visual disturbance in both eyes. The best-corrected visual acuity was 0.8 in the right eye and 0.6 in the left eye. Bilateral cortical cataract was observed on slit-lamp examination, and no other ophthalmic abnormalities were found. Potential risk factors for cataract were investigated, including past medical and family history, revealing a 20-year history of oral clonazepam (0.5-1 mg/day), for the neurological diagnosis of "chorea of unknown etiology". Detailed medication history did not reveal long-term use of any other drugs which could have induced the cataract. CONCLUSIONS: Because clonazepam use may induce cortical cataract, regular ophthalmologic examinations are necessary during long-term oral psychotropic therapy.
Key Words: Benzodiazepine;Cataract;Clonazepam


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