J Korean Ophthalmol Soc > Volume 53(6); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(6):749-760.
DOI: https://doi.org/10.3341/jkos.2012.53.6.749    Published online June 15, 2012.
Effects of Temporary Amniotic Membrane Patch after Surgical Excision of Primary Pterygium.
Byoung Young Gu, Sang Bumm Lee
Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea. sbummlee@med.yu.ac.kr
원발군날개에 대한 군날개절제술 후 일시양막이식술의 효과
Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea
To investigate the clinical results, recurrence rates, and recurrence-related risk factors of temporary amniotic membrane patch (TAMP) after excision of primary pterygium. METHODS: Recurrence grade was evaluated for 73 eyes with a mean follow-up of 15.5 months (range 9 to 56 months). Surgical results were classified into surgical success (G0/G1), conjunctival recurrence (G2), and corneal recurrence (G3). Recurrence rates were analyzed based on gender, age, Tan's preoperative grading system, horizontal and vertical length of the preoperative pterygium, the corneal involvement size of the preoperative pterygium, planned or unplanned removal of amniotic membrane, and epithelial healing time. Using Kaplan-Meier survival analysis, the cumulative proportion of integrated G0/G1 was evaluated. RESULTS: In the postoperative grading, 58 (79.5%) and 9 (12.3%) eyes were graded as clinically recurrence-free G0 and G1, respectively; 4 (5.5%) and 2 (2.7%) eyes were graded as clinically recurrence-occurred G2 and G3, respectively. The cumulative proportion of integrated recurrence-free G0/G1 at 24 months after surgery was 0.83 +/- 0.08. T3 of Tan's preoperative grading system was identified as the only risk factor for recurrence above G1 through multivariate logistic regression analysis (p = 0.02). CONCLUSIONS: The recurrence rate of the present TAMP study showed better results in comparison with 9.1 to 56.1% of recurrence rates in other studies. The TAMP has advantages of surgical procedure with ease, low complications, and low recurrence rates. Therefore, after surgical excision of primary pterygium, the authors concluded the TAMP is highly recommended for good clinical outcomes and low recurrence rates.
Key Words: Amniotic membrane;Permanent amniotic membrane graft;Primary pterygium;Recurrence rate;Temporary amniotic membrane patch

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