J Korean Ophthalmol Soc > Volume 49(12); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(12):1888-1893.
DOI: https://doi.org/10.3341/jkos.2008.49.12.1888    Published online December 15, 2008.
The Effects of Cheap Tinted Contact Lenses on Corneal Swelling and Ocular Surface Inflammation.
Jong Suk Song, Hwa Lee, Jung Wan Kim, Mun Hee Chang, Suk Kyu Ha, Hyo Myung Kim
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. crisim@korea.ac.kr
국내의 저가 컬러 콘택트렌즈가 각막 부종 및 안구 표면 염증에 미치는 영향
송종석ㆍ이 화ㆍ김정완ㆍ장문희ㆍ하석규ㆍ김효명
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea
Abstract
PURPOSE
To evaluate the effects of cheap tinted contact lenses on corneal swelling and ocular surface inflammation, compared to hydrogel and silicone hydrogel contact lenses. METHODS: Forty eyes of 20 New Zealand white rabbits were randomly assigned to 4 groups. Two types of tinted contact lenses, hydrogel lenses, and silicone hydrogel lenses were each applied to 10 rabbit eyes. Corneal thickness and tear lactate dehydrogenase (LDH) activity were measured at 1 and 4 days after contact lens wear, and the inflammation of ocular surface was scored at 4 days after contact lens wear. The internal surface of the cheap tinted lens was examined with a scanning electron microscope to compare the surface quality between the tinted and non-tinted area. RESULTS: Although the corneal swelling of the silicone hydrogel lens group was significantly lower than the other 3 lens groups after contact lens wear (p<0.01), the common hydrogel lens group was not different from the 2 tinted contact lens groups (p>0.1). Tear LDH activity at 1 and 4 days after contact lens wear showed no significant difference among the 4 groups (p>0.29). The scores of ocular surface inflammation in the 2 tinted contact lens groups were greater than the hydrogel and silicone hydrogel lens groups (p=0.03). The scanning electron microscope revealed the internal surface of the tinted area in the tinted contact lens was coarse and irregular though the surface of the non-tinted area was relatively smooth. CONCLUSIONS: Regarding corneal swelling and tear LDH activity, the cheap tinted contact lenses used in Korea were not significantly different from the common hydrogel contact lenses. However, tinted contact lenses showed a greater tendency to provoke ocular surface inflammation than other lenses. The coarse and irregular surface of the tinted area in the tinted contact lens appears to play a role in provoking severe ocular surface inflammation.
Key Words: Corneal swelling;Lactate dehydrogenase;Ocular surface inflammation;Scanning electron microscope;Tinted contact lens


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