| Photodynamic Therapy for Chronic Central Serous Chorioretinopathy: Multicenter Study of 65 Cases. |
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Jaeryung Oh, Oh Woong Kwon, Min Ho Kim, Jong In Kim, Ha Kyoung Kim, Hyung Chan Kim, Dong Heun Nam, Kyu Hyung Park, Joon Hong Sohn, Boo Sup Oum, Seung Young Yu, Young Hee Yoon, Ill Han Yoon, Hee Sung Yoon, Jae Heung Lee, Jeong Hee Lee, Ji Eun Lee, Woo Hyok Chang, Sung Won Cho, Hee Seung Chin, Kuhl Huh, Hyung Woo Kwak |
1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
2Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
3Apgujung St. Mary's Eye Hospital, Seoul, Korea.
4Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Seoul, Korea.
5Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea.
6Department of Ophthalmology, Konkuk University College of Medicine, Seoul, Korea.
7Department of Ophthalmology, Gachon University Gil Medical Center, Incheon, Korea.
8Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
9HanGil Eye Hospital, Incheon, Korea.
10Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea.
11Department of Ophthalmology, KyungHee University College of Medicine, Seoul, Korea. pbloadsky@naver.com
12Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
13Department of Ophthalmology, College of Medicine, Inje Universtiy, Pusan, Korea.
14Sungmo Eye Hospital, Pusan, Korea.
15Department of Ophthalmology, College of Medicine, Ewha Womans University, Seoul, Korea.
16Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea.
17Department of Ophthalmology, Inha University School of Medicine, Incheon, Korea. |
| 만성중심장액맥락망막병증에서의 광역학치료의 효과: 다기관 공동연구 |
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오재령1ㆍ권오웅2ㆍ김민호3ㆍ김종인4ㆍ김하경5ㆍ김형찬6ㆍ남동흔7ㆍ박규형8ㆍ손준홍9ㆍ엄부섭10ㆍ유승영11ㆍ윤영희12ㆍ윤일한13ㆍ윤희성14ㆍ이재흥4ㆍ이정희15ㆍ이지은10ㆍ장우혁16ㆍ조성원4ㆍ진희승17ㆍ허 걸1ㆍ곽형우11 |
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Department of Ophthalmology, Korea University College of Medicine1, Seoul, Korea / Department of Ophthalmology, Yonsei University College of Medicine2, Seoul, Korea / Apgujung St. Mary's Eye Hospital3, Seoul, Korea / Department of Ophthalmology, Konyang University, Kim's Eye Hospital4, Seoul, Korea / Department of Ophthalmology, Hallym University College of Medicine5, Seoul, Korea / Department of Ophthalmology, Konkuk University College of Medicine6, Seoul, Korea / Department of Ophthalmology, Gachon University Gil Medical Center7, Incheon, Korea / Department of Ophthalmology, Seoul National University College of Medicine8, Seoul, Korea / HanGil Eye Hospital9, Incheon, Korea / Department of Ophthalmology, College of Medicine, Pusan National University10, Pusan, Korea / Department of Ophthalmology, KyungHee University College of Medicine11, Seoul, Korea, / Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center12, Seoul, Korea / Department of Ophthalmology, College of Medicine, Inje Universtiy13, Pusan, Korea Sungmo Eye Hospital14, Pusan, Korea / Department of Ophthalmology, College of Medicine, Ewha Womans University15, Seoul, Korea / Department of Ophthalmology, Yeungnam University College of Medicine16, Daegu, Korea / Department of Ophthalmology, Inha University School of Medicine17, Incheon, Korea |
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| Abstract |
PURPOSE
To determine the effect of photodynamic therapy (PDT) on patients with chronic central serous chorioretinopahty (CSC). METHODS: This was a retrospective multicenter study. We collected demographic and ophthalmic data for patients with chronic CSC who were treated with PDT from 16 institutions in Korea. The best corrected visual acuity (BCVA), ophthalmoscopic finding and optical coherence tomography at baseline and follow-up visits were compared longitudinally. RESULTS: Sixty-five eyes of 65 patients were recruited. Males (51 patients, 78.5%) outnumbered females (14 patients, 21.5%). The mean age was 46.4+/-10.0 years of age (28~69). By 1 month, mean BCVA improved from 0.47 to 0.37 (logarithm of the minimum angle of resolution) (P <0.01). This BCVA increased throughout 6 months. Subretinal fluid resolved partially or completely in 89.1% of the patients. Central macular thickness (CMT) decreased from 303.4 to 168.7 micrometer. The amount of change in CMT after PDT was correlated to the female sex and prePDT CMT. At 3 months after PDT, the amount of change in BCVA was significantly related to that of change of CMT (p <0.05). Adverse events were reported in 4 cases, however, most were mild. CONCLUSIONS: PDT was effective and safe for treating chronic CSC. |
| Key Words:
BCVA;Chronic CSC;CMT;PDT |
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