J Korean Ophthalmol Soc > Volume 50(3); 2009 > Article
Journal of the Korean Ophthalmological Society 2009;50(3):418-423.
DOI: https://doi.org/10.3341/jkos.2009.50.3.418    Published online March 15, 2009.
Relationship Between Central Corneal Thickness and Retinal Nerve Fiber Layer Thickness in Glaucomatous Subject.
Kyung Rim Sung, Dong Yoon Kim, Yoon Pyo Nam
University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea. sungeye@gmail.com
녹내장안에서 망막신경섬유층두께와 중심각막두께의 상관관계 분석
성경림ㆍ김동윤ㆍ남윤표
University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea
Abstract
PURPOSE
To evaluate the correlation between central corneal thickness (CCT) and retinal nerve fiber layer thickness (RNFLT) as determined by optical coherence tomography (OCT) in glaucomatous subjects. METHODS: One hundred eyes diagnosed with glaucoma and 99 glaucoma suspect (GS) eyes were tested by visual field (VF), OCT, and ultrasonic pachymetry. The relationship between CCT and RNFLT measurements was assessed by Pearson correlation analysis. A mixed effect model was employed to determine the relationship between CCT and RNFLT in glaucoma and GS groups. We divided the patients into two groups depending on the thickness of their corneas: Thin (< 553.6 micrometer) and thick (> or = 553.6 micrometer), and compared three parameters: VF mean deviation (MD), pattern standard deviation (PSD), and RNFLT between the two groups. RESULTS: There were no significant correlations between CCT and RNFLT in any participant (R2=0.00, p=0.88). There was no significant relationship between CCT and RNFLT in glaucoma and GS groups (p=0.11, p=0.46). There were no statistically significant differences in MD, PSD, or RNFLT between the thin and thick cornea groups (p=0.38, 0.32, 0.44). CONCLUSIONS: CCT is not significantly associated with RNFLT in glaucoma and GS subjects.
Key Words: Central corneal thickness;Optical coherence tomography;Retinal nerve fiber layer thickness


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