J Korean Ophthalmol Soc > Volume 50(4); 2009 > Article
Journal of the Korean Ophthalmological Society 2009;50(4):558-564.
DOI: https://doi.org/10.3341/jkos.2009.50.4.558    Published online April 30, 2009.
Analysis of Localized Retinal Nerve Fiber Layer Defects not Detected by Optical Coherence Tomography.
Young Sang Han, Seung Youn Jea, Su Jin Kim, Joo Eun Lee, Ji Eun Lee, Gi Hong Koo
1Department of Ophthalmology, College of Medicine, Pusan National University, Busan, Korea.
2Lee Chun Sik's Eye Clinic, Busan, Korea. Jea-sy@hanmail.net
3Department of Ophthalmology, Maryknoll Hospital, Busan, Korea.
빛간섭단층촬영으로 발견하지 못한 국소적 망막신경섬유층 결손들의 분석
한영상1ㆍ제승연2ㆍ김수진1ㆍ이주은3ㆍ이지은1ㆍ구기홍1
Department of Ophthalmology, College of Medicine, Pusan National University1, Busan, Korea, Lee Chun Sik、s Eye Clinic2, Busan, Korea, Department of Ophthalmology, Maryknoll Hospital3, Busan, Korea
Abstract
PURPOSE
To analyze localized RNFL defect cases that were identified in retinal nerve fiber layer (RNFL) fundus photographs but not in optical coherence tomography (OCT). METHODS: Analysis of OCT scans and images was performed for 14 eyes (17 locations) that showed localized RNFL defects in RNFL fundus photographs but not in RNFL thickness average analysis. RESULTS: With respect to the range of RNFL defects, 41.2% were less than 10degrees, 47.0% were 11 to 20degrees, and 11.8% were 21 to 30degrees. In 71.4% of the RNFL cases the defects were less than 10degrees and the decrease of RNFL thickness was not readily observable on the OCT scan images. In all cases of RNFL defects in the 11 to 30degrees range the decrease in RNFL thickness could be assessed on the OCT scan images. Nonetheless, the decrease of RNFL thickness could not be seen on the OCT analysis images in which the results of the RNFL thickness made through an automated computer algorithm were displayed. CONCLUSIONS: The range of localized RNFL defects that were difficult to detect with OCT consisted of those cases that were almost less than 20degrees. The limitations of the OCT scan itself in patients with RNFL with an angular width defect less than 10degrees and the problems of RNFL thickness analysis processing in patients with an angular width of 11 to 30degrees may decrease the sensitivity of OCT in diagnosing RNFL defects.
Key Words: Optical coherence tomography;RNFL defect;RNFL fundus photograph


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