The Effects of Sutureless Faden Operation With Several Materials in Rabbit Models. |
Jeong Hun Seo, Seong Jun Lee, Ok Jun Lee, Mi Young Choi |
1Department of Ophthalmology, Chungbuk National University College of Medicine; Chungbuk National University Medical Research Institute, Cheongju, Korea. mychoi@chungbuk.ac.kr 2Lee's eye clinic, Daejon, Korea. 3Department of Pathology, Chungbuk National University College of Medicine; Chungbuk National University Medical Research Institute, Cheongju, Korea. |
토끼에서 여러 방법을 이용한 무봉합 뒤고정술의 효과 |
서정훈1ㆍ이성준2ㆍ이옥준3ㆍ최미영1 |
Department of Ophthalmology, Chungbuk National University College of Medicine; Chungbuk National University Medical Research Institute1, Cheongju, Korea Lee's eye clinic2, Daejon, Korea Department of Pathology, Chungbuk National University College of Medicine; Chungbuk National University Medical Research Institute3, Cheongju, Korea |
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Abstract |
PURPOSE To investigate the effects of sutureless faden operation to eliminate suture-related perioperative risks in a rabbit model. METHODS: Twenty-eighty superior recti muscles of 14 rabbits were subjected to faden operation, at a distance of 6 mm from the insertion of the muscle. They were divided into four groups of 7 muscles each: group A, Beriplast-P; group B, Bard(R) mesh (12x2 mm); group C, Surgipro(R) mesh (6x2 mm); group D, Surgipro(R) mesh (6x6 mm). Rabbits were sacrificed and the eyes were enucleated. The operative field was examined upon dissection, 4 weeks after the surgery. Histopathologic sections were examined for the degree (grade 0 to 4) of inflammation, fibrosis, atrophy and/or degeneration of muscle fiber. RESULTS: Grossly, there was a mild adhesion at the myopexy site in group A, while there was greater adhesion at the myopexy site in groups B, C and D. Group B produced a pronounced adhesion, and the mesh firmly adhered to the sclera as well as to adjacent tissue. Upon histologic examination, group A showed a mild inflammatory reaction and fibrosis, whereas groups B and D showed a moderate inflammatory reaction and fibrosis. The degree of fibrosis in group D was more severe than that in group A (p<0.008), and there was no statistical significance among the other groups (p>0.05). There was atrophy and degeneration in the muscle fiber in all groups, with the exception of group D. CONCLUSIONS: In the rabbit model, 6x6 mm sized Surgipro(R) mesh may be the best material in sutureless faden operation. |
Key Words:
Bard(R) mesh;Beriplast-P(R);Fadenoperation;Surgipro(R) mesh;Sutureless strabismus surgery |
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