Retinal Vasculopathy as First Manifestation of Chronic Myelogenous Leukemia.

Kim, In Tae; Kwon, Jin Woo

doi:2009.50.9.1418

J Korean Ophthalmol Soc > Volume 50(9); 2009 > Article

Case Report

Journal of the Korean Ophthalmological Society 2009;50(9):1418-1422.
DOI: https://doi.org/10.3341/jkos.2009.50.9.1418 Published online September 15, 2009.

Retinal Vasculopathy as First Manifestation of Chronic Myelogenous Leukemia.

In Tae Kim, Jin Woo Kwon

Department of Ophthalmology and Visual Science, St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. kimintae@catholic.ac.kr

만성 골수성 백혈병의 첫 번째 임상증상으로 나타난 망막 혈관병증 1예

김인태ㆍ권진우

Department of Ophthalmology and Visual Science, St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea

Abstract

PURPOSE
To present a case of bilateral retinal vasculopathy as the first manifestation of chronic myelogenous leukemia. CASE SUMMARY: A 59-year-old man with no medical history such as diabetes, hypertension and no ocular history complained of decreased visual acuity for 1 month. Fundus examinations showed diffuse multiple dot and blot hemorrhages over the panretina of both eyes and vessels showed tortuous vascular changes. The fluorescein angiogram was evaluated, and showed diffuse microaneurysms at the peripheral retina and posterior pole. Hematologic and biochemical examinations as well as a carotid sonogram were performed based on the possibility of systemic disease. The patient showed hematologic abnormality and therefore was transferred to internal medicine for diagnosis of chronic myelogenous leukemia. CONCLUSIONS: The authors examined a chronic leukemia patient, who showed bilateral retinal vasculopathy as the first manifestation of chronic myelogenous leukemia. This case shows the importance of considering the possibility of systemic disease.

Key Words: Chronic myelogenous leukemia;Retinal vasculopathy in leukemia