| The Relationship Between Intraocular Pressure and Visual Field Defect Progression in Normal-tension Glaucoma. |
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Eui Seok Han, Moon Jung Kim, Ki Ho Park |
1Jeju-si Seobu Public Health Center, Jeju, Korea.
2Kangdong Kong Eye Center, Seoul, Korea.
3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. kihopark@snu.ac.kr
4Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. |
| 정상안압녹내장에서 안압과 시야결손진행의 관계 |
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한의석1ㆍ김문정2ㆍ박기호3,4 |
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Jeju-si Seobu Public Health Center1, Jeju, Korea Kangdong Kong Eye Center2, Seoul, Korea / Department of Ophthalmology, Seoul National University College of Medicine3, Seoul, Korea / Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute4, Seoul, Korea |
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| Abstract |
PURPOSE
To investigate the relationship between intraocular pressure (IOP) and visual field defect progression (VFP) in normaltension glaucoma (NTG). METHODS: We reviewed the records of patients who were enrolled according to the following inclusion criteria: at least one IOPmeasurement at every section, which was divided into four sections (90 minutes) by IOP measurement time and a follow-up for 2 years or more. Patients were divided into VFP (n=9) and non-visual field defect progression (NVFP, n=28) groups. The baseline IOP was defined as an average IOP measured five times with 90-minute intervals before treatment. The maximal, minimal and mean IOPs were defined as the highest, lowest and average IOPs among all checked IOPs during follow-up. IOP fluctuation was defined as the difference between the maximal and minimal IOPs. The section IOP was defined as an average IOP among all checked IOPs in each section, and section IOP fluctuation was the difference between the highest and lowest section IOPs. We reviewed and compared the IOP indices of the two groups and the risk factors, including hypertension, diabetes, migraine, familial history of glaucoma, disc hemorrhage, and number of eyedrops. RESULTS: Thirty-seven eyes with an average follow-up of 50.4+/-18.9 months were included. The baseline and the maximal IOPs were higher than those of the NVFP group (p=0.001 and 0.032, respectively), but the mean, minimal and IOP fluctuations were not different (all, p>0.05). All section IOPs, section IOP fluctuations and other risk factors were not different (all, p>0.05). CONCLUSIONS: The baseline and the highest IOPs were a risk factor of VFP in NTG. |
| Key Words:
Baseline intraocular pressure;Intraocular pressure;Maximal intraocular pressure;Normal-tension glaucoma;Visual field defect progression |
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