Performance of Humphrey Matrix Frequency Doubling Technology Perimetry and Standard Automated Perimetry Global Indices.

Nam, Yoonpyo; Kang, Sung Yong; Park, Seong Bae; Sung, Kyung Rim; Kook, Michael S

doi:2009.50.11.1680

J Korean Ophthalmol Soc > Volume 50(11); 2009 > Article

Original Article

Journal of the Korean Ophthalmological Society 2009;50(11):1680-1685.
DOI: https://doi.org/10.3341/jkos.2009.50.11.1680 Published online November 15, 2009.

Performance of Humphrey Matrix Frequency Doubling Technology Perimetry and Standard Automated Perimetry Global Indices.

Yoonpyo Nam, Sung Yong Kang, Seong Bae Park, Kyung Rim Sung, Michael S Kook

¹Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea. sungeye@gmail.com
²Department of Ophthalmology, CHA University, CHA Bundang medical center, Seongnam, Korea.

험프리매트릭스 주파수배가시야검사법과 표준 자동시야검사법의 검사 지표에 대한 비교 분석

남윤표¹ㆍ강성용¹ㆍ박성배²ㆍ성경림¹ㆍ국문석¹

Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea

Abstract

PURPOSE
To evaluate and compare the diagnostic performance of Humphrey Matrix frequency doubling technology perimetry (Matrix) global indices with standard automated perimetry (SAP) for glaucoma discrimination. METHODS: Forty-seven healthy and 63 glaucomatous subjects were included in this study. Glaucoma was defined as having glaucomatous optic disc and glaucomatous visual field defect. Correlations of mean deviation (MD) and pattern standard deviation (PSD) between Matrix and SAP were evaluated. Areas under receiver operating characteristic curves (AUCs) for discriminating healthy from glaucoma, sensitivity, and cut-off value at fixed specificity of MD and PSD were determined in Matrix and SAP. RESULTS: MD and PSD from Matrix were highly correlated with SAP data in glaucomatous eyes (r=0.80, 0.69 p<0.001, <0.001). The AUCs of MD and PSD from Matrix (0.941, 0.921) were of comparable diagnostic capability to SAP data (0.876, 0.923, p=0.068, 0.927). The sensitivity at 90% specificity of MD was 67.9% in SAP, 76.4% in Matrix, with the cut off value of MD at 90% specificity at -3.10dB in SAP and -3.72dB in Matrix. CONCLUSIONS: MD and PSD data from Matrix and SAP significantly correlated in glaucomatous eyes and showed similar diagnostic performance for discriminating healthy from glaucoma however, both MD and PSD are scaled differently on SAP and Matrix, which suggests that application of these parameters in a manner similar to that used in SAP should be employed with caution.

Key Words: Glaucoma;Global index;Visual field