| Electrophysiological and Morphological Changes After Intravitreal Bevacizumab Injection with Macular Edema or Choroidal Neovascularization. |
|
Hyun Joon Lee, Joo Youn Park, Young Hoon Ohn |
1Department of Ophthalmology, Soonchunhyang University College of Medicine, Cheonan, Korea.
2Department of Ophthalmology, Soonchunhyang University College of Medicine, Bacheon, Korea. yhohn@schbc.ac.kr |
| 황반부종 및 맥락막신생혈관 환자에서 유리체강내 베바시주맙 주입술 후의 기능 및 형태적 변화 |
|
이현준1ㆍ박주연2ㆍ온영훈2 |
|
Department of Ophthalmology, Soonchunhyang University College of Medicine1, Cheonan, Korea Department of Ophthalmology, Soonchunhyang University College of Medicine2, Bacheon, Korea |
|
|
| Abstract |
PURPOSE
To evaluate the functional and anatomical statuses of macula with multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) for the treatment of patients with macular edema after intravitreal bevacizumab injection. METHODS: Patients were injected with intravitreal bevacizumab (1.875 mg/0.075 ml) for macular edema with choroidal neovascularization (CNV), diabetic retinopathy and retinal vein occlusion. RESULTS: A total of 120 eyes (96 patients) were diagnosed with diabetic retinopathy, CNV with age-related macular degeneration and retinal vein occlusion. Visual acuity improved from logMAR 0.85+/-0.39 to 0.54+/-0.38 after intravitreal bevacizumab injection. The implicit time of P1 and N2 in mfERG decreased, and the amplitude of P1 showed a statistically significant increase. Central macular thickness decreased from 374.4+/-135.2 micrometer to 249.0+/-72.0 micrometer. CONCLUSIONS: After intravitreal bevacizumab injection, functional and anatomical statuses of mfERG and OCT improved. This study demonstrates a method for utilizing mfERG to assess the effectiveness of treatments such as bevacizumab. |
| Key Words:
Choroidal neovascularization;Intravitreal Bevacizumab injection;Macular edema;Multifocal electroretinogram |
|
PDF Links
Full text via DOI
Download Citation
