A Case of Candida Parapsilosis Keratitis With Atypical Presentation.

Kim, Hoon Dong; Kim, So Young; Jung, Moon Sun

doi:2010.51.1.136

J Korean Ophthalmol Soc > Volume 51(1); 2010 > Article

Case Report

Journal of the Korean Ophthalmological Society 2010;51(1):136-140.
DOI: https://doi.org/10.3341/jkos.2010.51.1.136 Published online January 15, 2010.

A Case of Candida Parapsilosis Keratitis With Atypical Presentation.

Hoon Dong Kim, So Young Kim, Moon Sun Jung

Department of Ophthalmology, College of Medicine, Soonchunhyang University, Cheonan, Korea. greenizy@lycos.co.kr

비전형적인 임상양상을 보인 칸디다 파라프실로시스 각막염 1예

김훈동ㆍ김소영ㆍ정문선

Department of Ophthalmology, College of Medicine, Soonchunhyang University, Cheonan, Korea

Abstract

PURPOSE
To report a case of Candida parapsilosis keratitis with atypical presentation demonstrated by subepithelial white dot deposits without peripheral inflammatory reaction. CASE SUMMARY: A 45-year-old woman with Stevens-Johnson syndrome had used topical corticosteroid and bandage contact lens due to recurrent epithelial defect and keratitis. Multiple subepithelial white dot deposits were revealed on the central corneal area without surrounding inflammation. The corneal lesion was improved after epithelial debridement with topical antibiotics and steroid eyedrops. A few months later, however, the corneal lesion recurred. Smear cytology was performed, and yeast-formed fungi and pseudohyphae were found. C. parapsilosis was identified in the culture study. Therefore, the topical steroid was withdrawn and 0.15% topical Amphotericin was applied. The corneal lesion improved and corneal opacity did not progress. CONCLUSIONS: The case reported in this study is C. parapsilosis keratitis with multiple subepithelial white dot deposits without typical presentations of fungal kertitis. Although no typical infectious indication was evident, infection should be suspected in patients who show abnormal corneal lesion under immunosuppressive treatment.

Key Words: Candida parapsilosis;Keratitis;Subepithelial deposit