Fibrous Encapsulation of Biodegradable Collagen Matrix After Trabeculectomy: A Case Report.

Hong, Sojin; Lee, Jong Rak; Kim, Yeon Deok; Choi, Jin Young; Choi, Jaewan

doi:2010.51.4.631

J Korean Ophthalmol Soc > Volume 51(4); 2010 > Article

Case Report

Journal of the Korean Ophthalmological Society 2010;51(4):631-635.
DOI: https://doi.org/10.3341/jkos.2010.51.4.631 Published online April 15, 2010.

Fibrous Encapsulation of Biodegradable Collagen Matrix After Trabeculectomy: A Case Report.

Sojin Hong, Jong Rak Lee, Yeon Deok Kim, Jin Young Choi, Jaewan Choi

Department of Ophthalmology, Han Gil Eye Hospital, Incheon, Korea. deskshot@naver.com

섬유주절제술 후 생체 분해성 콜라겐 기질의 섬유성 피막형성 1예

홍소진ㆍ이종락ㆍ김연덕ㆍ최진영ㆍ최재완

Department of Ophthalmology, Han Gil Eye Hospital, Incheon, Korea

Abstract

PURPOSE
Recently, biodegradable collagen matrix has been used as a possible substitute for anti-metabolite in trabeculectomy in order to control the responsiveness of the wound healing process. This paper reports a case of encapsulation of the biodegradable collagen matrix after trabeculectomy. CASE SUMMARY: We conducted a fornix-based trabeculectomy on a 58-year-old man with medically uncontrollable steroid-induced glaucoma. We implanted biodegradable collagen matrix onto the sclera flap beneath the conjunctiva. Immediately after the surgery, we observed a localized bleb with high elevation. In the three months of follow-up, the bleb became encapsulated, and an increase in intraocular pressure was noted. During the wound revision, encapsulated material surrounded by thick fibrous membrane was found and removed from the subconjunctival space, followed by biopsy. Biopsy results demonstrated that amorphous collagenous material was surrounded by spindle and inflammatory cells. CONCLUSIONS: It is important to note that the fibrous encapsulation of collagen material is a possible complication of biodegradable collagen matrix-augmented trabeculectomy.

Key Words: Biodegradable collagen matrix;Complication;Ologen;Trabeculectomy