Analysis of Various Artifacts Produced by Spectral-Domain Optical Coherence Tomography Based on Macular Pathologies. |
Yong Woon Shin, Ju Hyang Lee, Jae Yeon Jun, Yumi Song, Hee Yoon Cho, Byung Ro Lee |
Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea. brlee@hanyang.ac.kr |
황반질환에 따른 스펙트럼 영역 빛간섭단층촬영의 다양한 오류 분석 |
신용운ㆍ이주향ㆍ전재연ㆍ송유미ㆍ조희윤ㆍ이병로 |
Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea |
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Abstract |
PURPOSE To report the frequency, severity and various types of artifacts associated with spectral-domain optical coherence tomography (SD-OCT) based on macular pathologies. METHODS: Data was collected retrospectively from 116 eyes of 116 subjects. SD-OCT (3D-1000, Topcon Corp., Japan) imaging was performed in 40 healthy eyes, 45 eyes with intraretinal pathology (IRP) and 31 eyes with subretinal pathology (SRP). The scan protocol was 12x6 mm radial scan. The frequency and types of artifacts were investigated in each scan and were analyzed based on macular disease. Additionally, the effect of artifacts on the measurement of macular thickness was studied. RESULTS: Errors occurred in 77 eyes (66.38%). Inner retinal boundary misidentification (IRBM) was the most common error (25.86%), with the frequencies of other types of artifacts being 10.34% for off-center fixation, 15.52% for degraded image and 8.6% for outer retinal boundary misidentification (ORBM). The overall error rate of SD-OCT in the retinal pathology group was much higher than that in the normal group. Macular thickness was underestimated in the IRP group because the outer retinal boundary of the IRP group tended to be misidentified toward the inner retina (p<0.01). CONCLUSIONS: SD-OCT can frequently cause various types of artifacts in patients with macular disease. When interpreting OCT images, the artifacts of SD-OCT should be considered in order to obtain accurate macular thickness and to prevent erroneous clinical decisions. |
Key Words:
Artifact;Macular disease;Segmentation error;Spectral domain optical coherence tomography |
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