Clinical Manifestation in Rhino-Orbito-Cerebral Mucormycosis.

Song, Yoo Mi; Kang, Il Bong; Shin, Sun Young

Case Report

Journal of the Korean Ophthalmological Society 2007;48(4):593-598.
Published online April 30, 2007.

Clinical Manifestation in Rhino-Orbito-Cerebral Mucormycosis.

Yoo Mi Song, Il Bong Kang, Sun Young Shin

Department of Ophthalmology, Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Korea. eyeshin@hanyang.ac.kr

비안와두부형 뮤코르진균증의 임상양상 3예

송유미,강일봉,신선영

Department of Ophthalmology, Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Korea

Correspondence: Yoo Mi Song, M.D

Abstract

PURPOSE
To report upon several cases of rhino-orbito-cerebral mucormycosis with variable clinical manifestations including ocular symptoms. METHODS: We documented three patients with rhino-orbital-cerebral mucormycosis and uncontrolled diabetes. RESULTS: The patients presented variable ophthalmic symptoms including blepharoptosis, ophthalmoplegia, visual disturbance, visual field defect and ocular pain. Despite administration of an antifungal agent within two days, all of the patients died. CONCLUSIONS: We reported the cases of three patients with rhino-orbito-cerebral mucormycosis presenting ophthalmic symptoms with a literature review. Variable initial symptoms were emphasized in making diagnosis of rhino-orbito-cerebral mucormycosis.

Key Words: Orbital cellulitis;Rhino-orbital-cerebral mucormycosis