Serous Retinal Detachment in Patients with Choroidal Neovascularization Following Photodynamic Therapy.

Kim, Cinoo; Chung, Hum; Heo, Jang Won

doi:2007.48.10.1354

J Korean Ophthalmol Soc > Volume 48(10); 2007 > Article

Original Article

Journal of the Korean Ophthalmological Society 2007;48(10):1354-1361.
DOI: https://doi.org/10.3341/jkos.2007.48.10.1354 Published online October 31, 2007.

Serous Retinal Detachment in Patients with Choroidal Neovascularization Following Photodynamic Therapy.

Cinoo Kim, Hum Chung, Jang Won Heo

¹Department of Ophthalmology, Seoul National University College of Medicine Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
²Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea. hjwin@lycos.co.kr

맥락막신생혈관의 광역학치료후 발생한 장액성 망막박리

김신우¹,정흠¹,허장원²

Department of Ophthalmology, Seoul National University College of Medicine Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute¹, Seoul, Korea Department of Ophthalmology, Seoul National University Boramae Hospital², Seoul, Korea

Correspondence: Jang Won Heo, M.D.

Abstract

PURPOSE
To quantify the development and resolution of serous retinal detachment in patients with choroidal neovascularization (CNV) following photodynamic therapy (PDT). METHODS: Six eyes of five patients who developed serous retinal detachment two days after PDT were included in this study. Retinal thickness was measured by optical coherence tomography (OCT) before PDT, and at two days, seven days, and three weeks after PDT. The number of PDT and the greatest linear dimension (GLD) of the CNV lesion were recorded. RESULTS: Serous retinal detachment was demonstrated on OCT at two days after PDT. Retinal elevation increased significantly from 313.2 micrometer before PDT to 640.7 micrometer two days after PDT (P<0.01); elevation and decreased to 303.2 micrometer seven days after PDT, and decreased to 223.4 micrometer three weeks after PDT. The mean number of PDT treatments 2.0 (range: 1~3), and the mean GLD before PDT was 3122.8+/-1275.9 micrometer. CONCLUSIONS: This study suggest that serous retinal detachment in patients with CNV may develop following PDT but may also resolve spontaneously seven days after PDT.

Key Words: Choroidal neovascularization;Photodynamic therapy;Serous retinal detachment