J Korean Ophthalmol Soc > Volume 48(10); 2007 > Article
Journal of the Korean Ophthalmological Society 2007;48(10):1433-1437.
DOI: https://doi.org/10.3341/jkos.2007.48.10.1433    Published online October 31, 2007.
Bilateral Central Retinal Vein Occlusion in Primary Antiphospholipid Syndrome.
Sang Hyuk Kim, Jung Yeul Kim
1Department of Ophthalmology, College of medicine,Chungnam National University, Daejeon, Korea. kimjy@cnu.ac.kr
2Chungnam National University Research Institute for Medical Sciences, Daejeon, Korea.
원발성 항인지질증후군에서 발생한 양안의 망막중심정맥폐쇄
김상혁1,김정열1,2
Department of Ophthalmology, College of medicine,Chungnam National University1, Daejeon, Korea1 Chungnam National University Research Institute for Medical Sciences2, Daejeon, Korea1
Correspondence:  Jung Yeul Kim, M.D.
Abstract
PURPOSE
To Report a case of bilateral central retinal vein occlusion (CRVO) caused by primary antiphospholipid syndrome. METHODS: A 38-year-old male is referred to the department of ophthalmology for the bilateral visual loss. RESULTS: On initial visit, both visual acuity was 0.3. Upon consider changing to fundoscopic examination, the patient was diagnosed with bilateral CRVO. We performed hematologic tests including thrombophilia examination. There were no abnormal findings on routine hematologic tests. Antinuclear antibody and rheumatoid factor were negative but anticardiolipin antibodies presented high titer, on two occasions six weeks apart. We prescribed oral aspirin and performed intravitreal bevacizumab injection under the diagnosis of bilateral CRVO in primary antiphospholipid syndrome. CONCLUSIONS: It may be necessary to check antiphospolipid antibody in cases of bilateral CRVO in young patients without medical problem.
Key Words: Antiphospholipid syndrome;Anticardiolipin antibody;Central retinal vein occlusion


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