J Korean Ophthalmol Soc > Volume 48(11); 2007 > Article
Journal of the Korean Ophthalmological Society 2007;48(11):1487-1493.
DOI: https://doi.org/10.3341/jkos.2007.48.11.1487    Published online November 30, 2007.
Fluorescein Angiographic Features in Central Retinal Vein Occlusion With and Without Optic Nerve Head Swelling.
Youn Hui Kim, Sang Kook Kim
Department of Ophthalmology, School of Medicine, Chungbuk National University, Chungbuk, Korea. simple521@chungbuk.ac.kr
망막중심정맥폐쇄에서 시신경유두부종의 유무에 따른 형광안저혈관조영소견
김연희,김상국
Department of Ophthalmology, School of Medicine, Chungbuk National University, Chungbuk, Korea
Correspondence:  Sang Kook Kim, M.D., Ph.D.
Abstract
PURPOSE
To investigate the characteristics of fluorescein angiograms (FAG) of the optic nerve head and retina according to the presence of optic nerve head swelling (ONHS) in central retinal vein occlusion (CRVO). METHODS: The records of 69 eyes were reviewed, confirmed with the diagnosis of CRVO, and compared for several features according to the presence of ONHS. The best-corrected visual acuities and intraocular pressures were recorded and patterns of retinal hemorrhage were described. The presence of fluorescein filling defects of the optic disc, time till fluorescein started to fill at the optic disc, arteriovenous transit time, and nonperfused areas were assessed using FAG. RESULTS: Forty-one patients without ONHS (group 1) and 28 patients with ONHS (group 2) were included. The mean ages for groups 1 and 2 were 61.4 and 56.9 years, respectively, and there was no significant difference the mean ages between the groups. The fluorescein filling defect of the optic disc was seen more often in group 1 (n=13) than in group 2 (n=2). Marginal irregularity of the foveal avascular zone due to perifoveal capillary drop out was seen significantly more often in group 1 (n=12) than in group 2 (n=2). CONCLUSIONS: Fluorescein filling defects of the optic disc and perifoveal capillary drop out were more frequently seen in CRVO patients without ONHS. However, longitudinal studies are needed to confirm the prognostic value of ONHS and the correlation of filling defects with progressive optic neuropathy in CRVO.
Key Words: Central retinal vein occlusion;Fluorescein filling defect;Optic nerve head swelling


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