J Korean Ophthalmol Soc > Volume 48(12); 2007 > Article
Journal of the Korean Ophthalmological Society 2007;48(12):1731-1735.
DOI: https://doi.org/10.3341/jkos.2007.48.12.1731    Published online December 31, 2007.
A Case of Toxic Amblyopia Caused by Methanol Intoxication.
Jae Soon Bang, Hong Seok Yang, Seung Soo Rho, Yoon Hee Chang
Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea. yhchang@ajou.ac.kr
메탄올에 의한 중독성 약시의 치험 1예
방재순,양홍석,노승수,장윤희
Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea
Correspondence:  Yoon-Hee Chang, M.D.
Abstract
PURPOSE
To report a case of visual improvement in methanol poisoning treated with intravenous methylprednisolone. CASE SUMMARY: A 64-year-old man presented with decreasing vision in both eyes after ingesting a car window cleanser. His initial visual acuity was the ability to count fingers in the right eye and hand motion in the left eye. The patient received intravenous methylprednisolone (1.0 gram), slowly over 1 hour. The same dose of methyl prednisolone was repeated on the second and third day. Then, oral prednisolone was given and tapered over a period of 7 weeks. On the 5th day after treatment, there was an improvement in the visual acuity of the right eye to 0.4 but no improvement of vision was observed in the left eye. On 16th day after treatment, the visual acuity was 0.7 in the right eye and counting fingers in the left eye. At 2 months after ingestion, the visual acuity of the right eye returned to 1.0 with no improvement in the left eye. Optic disc pallor was suspected and P100 delay was observed in the left eye with VEP showing a favorable outcome in the right eye. CONCLUSIONS: A visual improvement of 1 eye was observed in methanol poisoning treated with intravenous methylprednisolone.
Key Words: Amblyopia;Intoxication;Methanol;Steroid


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