J Korean Ophthalmol Soc > Volume 49(4); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(4):677-680.
DOI: https://doi.org/10.3341/jkos.2008.49.4.677    Published online April 15, 2008.
A Case of Post-traumatic Necrobiotic Xanthogranuloma of the Orbit.
Hyun Joon Choi, Hee Jung Kwon, Hye Young Kim
National Health Insurance Corporation Ilsan Hospital, Gyeonggi, Korea. khyeye@hanmail.net
외상 후 발생한 안와 생괴사 황색육아종 1예
최현준ㆍ권희정ㆍ김혜영
National Health Insurance Corporation Ilsan Hospital, Gyeonggi, Korea
Abstract
PURPOSE
To investigate the role of nitric oxide (NO) on the migration of cultured human Tenon's capsule PURPOSE: Necrobiotic xanthogranuloma is a very rare disease characterized by the presence of yellow subcutaneous skin lesions and systemic paraproteinemia. We report a case of post traumatic necrobiotic xanthograuloma that presented with a preseptal mass. CASE SUMMARY: A 31-year-old man presented with ptosis and a mass on the left superior orbit that developed after trauma 3 weeks prior to admission. A computed tomography scan showed a contrast-enhancing preseptal mass, and surgical exploration was performed. CONCLUSIONS: Histopathological examination revealed a tumor that had all the major features of necrobiotic xanthogranuloma, including fat necrosis with granulomatous inflammation, giant multinucleated cells, foamy cells, and several lymphoid follicles with germinal centers. Hematologic evaluation revealed polyclonal gammopathy.
Key Words: Necrobiotic xanthogranuloma;Orbital tumor;Paraproteinemia;Polyclonal gammopathy


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