A Case of Sarcoidosis Presented as Multiple Conjunctival and Nasal Mucosal Nodule. |
In Cheon You, Hyung Jin Moon, Gwi Hyeong Mun, Sang Chul Im, Kyung Chul Yoon |
1Department of Ophthalmology, Chonbuk National University, College of Medicine, Chonbuk, Korea. you2ic@paran.com 2Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. 3Department of Otorhinolaryngology, Chonnam National University Medical School, Gwangju, Korea. |
결막과 비점막에 다발성 작은결절로 발현된 사르코이드증 1예 |
유인천1ㆍ문형진2ㆍ문귀형2ㆍ임상철3ㆍ윤경철2 |
Department of Ophthalmology, Chonbuk National University, College of Medicine1, Chonbuk, Korea / Department of Ophthalmology, Chonnam National University Medical School2, Gwangju, Korea / Department of Otorhinolaryngology, Chonnam National University Medical School3, Gwangju, Korea |
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Abstract |
PURPOSE Sarcoidosis is a noncaseating granulomatous disorder that can affect any organ. In its early phase, sarcoidosis is clinically similar to tuberculosis. We report a case of sarcoidosis diagnosed through ocular and systemic evaluations in a patient who developed multiple conjunctival nodules during antituberculous treatment for nasal mucosal nodules. CASE SUMMARY: A 37-year-old woman who had been on antituberculosis medications for 9 months because of multiple nasal mucosal nodules was referred for conjunctival hyperemia and the multiple nodules. The ocular examination revealed multiple conjunctival nodules in the upper and lower fornices. Biopsy and systemic evaluations were performed. A conjunctival biopsy specimen showed noncaseating granulomatous inflammation compatible with sarcoidosis. Laboratory tests revealed hypercalciuria and increased levels of ACE. Chest computed tomography showed bilateral hilar and mediastinal lymphadenopathy. Subconjunctival steroid injection was done for the conjunctival nodules and systemic steroid treatment was started as well. Complete resolution of conjunctival lesions was obtained. CONCLUSIONS: In cases of chronic, multiple conjunctival and nasal mucosal nodules, sarcoidosis should be considered in the differential diagnosis. |
Key Words:
Conjunctiva;Corticosteroid;Nasal mucosa;Sarcoidosis |
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