Photodynamic Therapy with Vertepofin for Short Time for Chronic Central Serous Chorioretinopathy. |
Jung Lim Kim, Hyun Woong Kim, Il Han Yoon |
1Department of Ophthalmology, College of Medicine, Inje University, Pusan, Korea. 2Ophthalmology Research Foundation, Inje University, Pusan, Korea. |
만성 중심장액맥락망막병증 환자에서 짧은 시간의 광역학치료의 효과 |
김정림ㆍ김현웅ㆍ윤일한 |
Department of Ophthalmology, College of Medicine, Inje University, Pusan, Korea, Ophthalmology Research Foundation, Inje University, Pusan, Korea |
Correspondence:
Jung Lim Kim, M.D. |
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Abstract |
PURPOSE To evaluate the clinical results of short duration photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC). METHODS: We retrospectively examined 15 eyes after PDT for chronic central serous chorioretinopathy. PDT for 83 seconds was evaluated for 8 eyes, and PDT for 60 seconds was evaluated for 7 eyes. Improvement in vision and changes in central macular thickness were evaluated with an optical coherence tomogram (OCT), and improvement in leaking was evaluated with a fluorescein angiogram (FA). Recurrence was also studied. RESULTS: Visual acuity improved from 0.39 to 0.57 (p=0.04), and the mean central macular thickness decreased from 426.29 micrometer to 184.71 micrometer (p<0.01) in 7 eyes treated with PDT for 60 seconds. There was no significant change in visual acuity between the two groups (p=0.77) or in central macular thickness (p=0.52). Central macular exudation resolved completely in all eyes. After PDT, there was no recurrence during the follow-up period. CONCLUSIONS: Short duration PDT with verteporfin appears to be a beneficial treatment option for patients with chronic CSC. |
Key Words:
Chronic central serous chorioretinopathy;Indocyanine green angiography;Optical coherence tomography;Photodynamic therapy |
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