J Korean Ophthalmol Soc > Volume 49(8); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(8):1289-1296.
DOI: https://doi.org/10.3341/jkos.2008.49.8.1289    Published online August 15, 2008.
Epidemiologic and Clinical Features of Uveal Melanoma in Korean Patients.
Jeong Hun Bae, Won Kyung Song, Hyoung Jun Koh, Oh Woong Kwon, Sung Chul Lee
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea. sunglee@yuhs.ac.kr
한국인에서 포도막흑색종의 역학과 임상양상
배정훈ㆍ송원경ㆍ고형준ㆍ권오웅ㆍ이성철
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea
Abstract
PURPOSE
To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients. METHODS: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively. RESULTS: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2+/-14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0+/-3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2+/-2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%). CONCLUSIONS: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated.
Key Words: Clinical feature;Epidemiology;Korean patients;Uveal melanoma


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