Epidemiologic and Clinical Features of Uveal Melanoma in Korean Patients. |
Jeong Hun Bae, Won Kyung Song, Hyoung Jun Koh, Oh Woong Kwon, Sung Chul Lee |
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea. sunglee@yuhs.ac.kr |
한국인에서 포도막흑색종의 역학과 임상양상 |
배정훈ㆍ송원경ㆍ고형준ㆍ권오웅ㆍ이성철 |
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea |
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Abstract |
PURPOSE To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients. METHODS: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively. RESULTS: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2+/-14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0+/-3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2+/-2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%). CONCLUSIONS: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated. |
Key Words:
Clinical feature;Epidemiology;Korean patients;Uveal melanoma |
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