Journal of the Korean Ophthalmological Society 2005;46(6):1073-1078.
Published online June 30, 2005.
Multiple Myeloma Presented With Unilateral Ptosis: A Case Report.
Min Joung Lee, Ho Kyung Choung, Sang In Khwarg, Hee Jin Yang
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
2Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea. hokyung@brm.co.kr
4Department of Neurosurgery, Seoul National University Boramae Hospital, Seoul, Korea.
단안의 안검하수를 주소로 발견된 다발성 골수종 1예
이민정1,2,정호경1,3,곽상인1,2,양희진4
Department of Ophthalmology, Seoul National University College of Medicine,1 Seoul, Korea Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital,2 Seoul, Korea Department of Ophthalmology, Seoul National University Boramae Hospital,3 Seoul, Korea Department of Neurosurgery, Seoul National University Boramae Hospital,4 Seoul, Korea
Correspondence:  Min-Joung Lee, M.D.1,2
Abstract
PURPOSE
As orbital involvement in multiple myeloma is rare, the correct diagnosis is usually difficult. We report a case of multiple myeloma which involved the orbit, and which presented with unilateral ptosis. METHODS: A 35-year-old man was referred for the evaluation of ptosis of the left eyelid for 1 month. The levator function was normal, and there was no proptosis. Orbital computerized tomography (CT) revealed an orbital mass lesion involving the superior orbital ridge with intracranial extension. RESULTS: Excisional biopsy was performed through craniotomy and superior orbitotomy. Histopathologic examination and immunostaining result suggested a diagnosis of a plasmacytoma. The diagnosis of multiple myeloma was confirmed through bone marrow aspiration and biopsy showing diffuse infiltration of plasma cells. CONCLUSIONS: We experienced a case of multiple myeloma, which is rare in the orbit presenting unilateral ptosis. In addition, the possibility of orbital mass should be considered as an unusual cause of unilateral, acquired, progressive ptosis.
Key Words: Multiple myeloma;Orbital mass;Plasmacytoma;Ptosis


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