Three Cases of Orbitofrontal Cholesterol Granuloma.

Chang, Ju Hee; Lee, Sang Hyeok; Chung, Wha Sun

Case Report

Journal of the Korean Ophthalmological Society 2005;46(7):1228-1234.
Published online July 31, 2005.

Three Cases of Orbitofrontal Cholesterol Granuloma.

Ju Hee Chang, Sang Hyeok Lee, Wha Sun Chung

¹Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea. shhlll@hanmail.net
²Dr. Chung's Eye Clinic, Daegu, Korea.

안와전두골에 발생한 콜레스테롤 육아종 3예

장주희¹,이상혁¹,정화선²

Department of Ophthalmology, Yeungnam University College of Medicine¹, Daegu, Korea Dr. Chung`s Eye Clinic², Daegu, Korea

Correspondence: Ju-Hee Chang, M.D.¹

Abstract

PURPOSE
To report three cases of orbitofrontal cholesterol granuloma. METHODS: The study subjects were three patients with chief complaints of proptosis and upgaze limitation of ocular movement. Exophthalmometric values were 4~8 mm by Hertel exophthalmometer. Orbital CT and MRI scans were taken in all patients, and regarded as orbitofrontal cholesterol granuloma. In all cases, excisional biopsy was done through the lateral approach. RESULTS: Orbital CT scan showed an isodense to hypodense, well-defined, homogeneous mass and osteolytic lesion in the adjacent superolateral bony orbit. Orbital MRI scan showed a mass with high signal intensity in both T1- and T2-weighted images. Histopathologically, the specimen showed numerous slits like cholesterol clefts surrounded by multinucleated, foreign body type, giant cells with hemosiderin pigments. CONCLUSIONS: Orbitofrontal cholesterol granuloma, although rare, has typical clinical and radiologic features. Surgical excision has a high success rate without recurrence.

Key Words: Cholesterol granuloma;Orbitofrontal bone;Proptosis