| Effect of Photodynamic Therapy and Intravitreal Triamcinolone Acetonide on Choroidal Neovascularization in Age-related Macular Degeneration. |
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Hyun Sub Oh, Mi In Roh, Sang Joon Oh, Sung Chul Lee, Won Young Lee, Oh Woong Kwon |
1The Insitiute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. owkwon0301@yumc.yonsei.ac.kr
2Department of Ophthalmology, Seoul Veterans Hospital, Seoul, Korea.
3Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea. |
| 연령관련황반변성에 의한 맥락막하신생혈관에서 광역학치료와 유리체강내 스테로이드주입술의 치료효과 |
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오현섭1,노미인1,오상준2,이성철1,이원영3,권오웅1 |
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The Insitiute of Vision Research Department of Ophthalmology, Yonsei University College of Medicine1, Seoul, Korea Department of Ophthalmology, Seoul Veterans Hospital2, Seoul, Korea Department of Microbiology, Yonsei University College of Medicine3, Seoul, Korea |
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Correspondence:
Hyun-Sub Oh, M.D.1 |
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| Abstract |
PURPOSE
To evaluate the safety and visual outcome of intravitreal triamcinolone acetonide combined with photodynamic therapy for subfoveal choroidal neovascularization in patients with age-related macular degeneration. METHODS: We evaluated 32 eyes of 32 patients with choroidal neovascularization due to age-related macular degeneration. The study group received photodynamic therapy and intravitreal triamcinolone acetonide (combined group), while the control group received photodynamic therapy only (PDT group). RESULTS: Three months after treatment, no difference was detected between the two groups in visual acuity changes (p>0.05), but the leakage in fluorescein angiography and macular edema in optical coherent tomography decreased (p<0.05) in the combined group. The retreatment rate in the combined group (6.0%) after 3 months was lower than that of the PDT group (53.3%). CONCLUSIONS: Photodynamic therapy with intravitreal triamcinolone acetonide to choroidal neovascularization reduced the retreatment rate at 3 months significantly. These results may have been be due to the short-term anti-inflammatory effect of steroids. |
| Key Words:
Age-related macular degeneration;Choroidal neovascularization;Intravitreal triamcinolone acetonide;Photodynamic therapy |
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