A Case of Keratoconjunctivitis Sicca Associated Idiopathic Hypereosinophilic Syndrome. |
Young Joo Shin, Sang Jin Kim, Won Ryang Wee, Yun Suk Chang |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. wrwee@snu.ac.kr 2Seoul National University Bundang Hospital, Seongnam, Korea. 3Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. |
과호산구증후군에서 발생한 건성각결막염 1례 |
신영주1,2,김상진1,위원량1,2,장윤석3 |
Department of Ophthalmology1 and Department of Internal Medicine3, Seoul National University College of Medicine, Seoul, Korea Seoul National University Bundang Hospital,2 Seongnam, Korea |
Correspondence:
Young-Joo Shin, M.D.1,2 |
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Abstract |
PURPOSE To report a case of the keratoconjunctivitis sicca (KCS) associated idiopathic hypereosinophilic syndrome (IHES). METHODS: We present a report and review of a 53-year-old man who suffered from IHES and KCS. The ocular examination showed conjunctival papillary hypertrophy, interpalpebral corneal and conjunctival punctate staining with fluorescein dye, and peripheral corneal neovascularization. His Schirmer I test results were nearly zero mm of wetting in both eyes. Impression cytology showed squamous metaplasia. RESULTS: He had treated with low dose systemic steroid since October 2003. Because he showed a side effect of steroid induced myopathy, we could not increase the dosage. We added topical steroid (Pred Forte(R)), conservative free artificial tear and topical antibiotics, after which his ocular condition improved. Neovascularization was regressed, punctate staining decreased, and his visual acuity increased to 20/25 2 months later. CONCLUSIONS: This case demonstrates that the KCS can be associated with IHES and be treated with systemic and topical steroid. |
Key Words:
Hypereosinophilic syndrome;Keratoconjunctivitis sicca |
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