A Case of Keratoconjunctivitis Sicca Associated Idiopathic Hypereosinophilic Syndrome.

Shin, Young Joo; Kim, Sang Jin; Wee, Won Ryang; Chang, Yun Suk

Case Report

Journal of the Korean Ophthalmological Society 2005;46(8):1401-1404.
Published online August 31, 2005.

A Case of Keratoconjunctivitis Sicca Associated Idiopathic Hypereosinophilic Syndrome.

Young Joo Shin, Sang Jin Kim, Won Ryang Wee, Yun Suk Chang

¹Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. wrwee@snu.ac.kr
²Seoul National University Bundang Hospital, Seongnam, Korea.
³Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

과호산구증후군에서 발생한 건성각결막염 1례

신영주^1,2,김상진¹,위원량^1,2,장윤석³

Department of Ophthalmology¹ and Department of Internal Medicine³, Seoul National University College of Medicine, Seoul, Korea Seoul National University Bundang Hospital,² Seongnam, Korea

Correspondence: Young-Joo Shin, M.D.^1,2

Abstract

PURPOSE
To report a case of the keratoconjunctivitis sicca (KCS) associated idiopathic hypereosinophilic syndrome (IHES). METHODS: We present a report and review of a 53-year-old man who suffered from IHES and KCS. The ocular examination showed conjunctival papillary hypertrophy, interpalpebral corneal and conjunctival punctate staining with fluorescein dye, and peripheral corneal neovascularization. His Schirmer I test results were nearly zero mm of wetting in both eyes. Impression cytology showed squamous metaplasia. RESULTS: He had treated with low dose systemic steroid since October 2003. Because he showed a side effect of steroid induced myopathy, we could not increase the dosage. We added topical steroid (Pred Forte(R)), conservative free artificial tear and topical antibiotics, after which his ocular condition improved. Neovascularization was regressed, punctate staining decreased, and his visual acuity increased to 20/25 2 months later. CONCLUSIONS: This case demonstrates that the KCS can be associated with IHES and be treated with systemic and topical steroid.

Key Words: Hypereosinophilic syndrome;Keratoconjunctivitis sicca