| Efficacy of Silicone Nasolacrimal Intubation with Mitomycin C Treatmentfor Treatment of Incomplete Nasolacrimal Duct Obstruction. |
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Deok Soo Kim, Yong Jae Lee |
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Department of Ophthalmology, University of Ulsan College of Medicine,Asan Medical Center, Seoul, Korea. yongjae@amc.seoul.kr |
| 코눈물관 부분폐쇄 치료시 마이토마이신 관류 여부에 따른 실리콘관 삽입술의 효과 |
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김덕수,이용재 |
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Department of Ophthalmology, University of Ulsan College of Medicine,Asan Medical Center, Seoul, Korea |
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Correspondence:
Deok Soo Kim, M.D. |
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| Abstract |
PURPOSE
To investigate the efficacy and safety of adjunctive Mitomycin C (MMC) during silicone intubation (SI) for treatment of acquired incomplete nasolacrimal duct obstruction (NLDO). METHODS: Nineteen eyes with incomplete NLDO underwent SI only (group I). 20 different eyes were administered adjunctive 0.4 mg/ml MMC for 4 minutes (group II). Diagnosis of incomplete NLDO was based upon subjective complaints of tearing, dye disappearance testing, clinical evidence of epiphora, and nasolacrimal duct irrigation. Follow-up examination was conducted at 1, 3, and 6 months. RESULTS: Follow-up ranged from 3 to 15 months (mean, 6.1 months). Twelve (63.1%) eyes in group I and 14 (70.0%) eyes in group II had a successful outcome and remained symptom-free. Four (21.1%) eyes in group I and three (15.0%) eyes in group II showed improvement but still experienced periodic epiphora. The difference was not statistically significant (p=0.873). CONCLUSIONS: SI as a treatment for incomplete NLDO provides complete relief or substantial improvement in a significant percentage of patients but MMC application during SI did not benefit outcome. |
| Key Words:
Mitomycin C;Nasolacrimal duct obstruction;Silicone intubation |
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