Clinical Analysis of Recurrent Vogt-Koyanagi-Harada Syndrome.

Kim, Min Jung; Cho, Nam Chun; Ahn, Min

Original Article

Journal of the Korean Ophthalmological Society 2006;47(2):227-234.
Published online February 28, 2006.

Clinical Analysis of Recurrent Vogt-Koyanagi-Harada Syndrome.

Min Jung Kim, Nam Chun Cho, Min Ahn

Department of Ophthalmology, Chonbuk National University, College of Medicine, Jeonju, Korea. cnauo@moak.chonbuk.ac.kr

재발성 보크트-고야나기-하라다 증후군에 대한 임상 분석

김민정,조남천,안민

Department of Ophthalmology, Chonbuk National University, College of Medicine, Jeonju, Korea

Correspondence: Min Jung Kim, M.D.

Abstract

PURPOSE
We analyzed the clinical features of patients with recurrent Vogt-Koyanagi-Harada(VKH) syndrome. METHODS: A retrospective chart review of 21 patients diagnosed with VKH syndrome between 1994 and 2004 was performed. We grouped the patients into two groups according to the duration of ocular inflammation. Group A included patients with recurrent ocular inflammation lasting 24 months or longer and Group B included those with a duration of less than 24 months. We compared the clinical manifestations, responses to treatment and complications. RESULTS: Group A had 7 patients and Group B had 14 patients. There were significant differences in initial visual acuity, the interval between ocular symptoms and treatment, total steroid dose, and complications. The average final visual acuity of Group A was 0.572 (0.2-1.0), which was relatively favorable. CONCLUSIONS: The initial visual acuity and the interval between ocular symptoms and treatment seemed to be important predictors. We conclude that aggressive treatment is necessary in recurrent VKH syndrome, as visual prognosis was relatively favorable despite the cost of the problems associated with high dose steroids and ocular complications.

Key Words: Ohno Type;Recurrent Vogt-Koyanagi-Harada Syndrome