Journal of the Korean Ophthalmological Society 2006;47(5):717-724.
Published online May 31, 2006.
Changes of Ocular Surface and Tear Film in Patients with Pinguecula and Pterygium.
Han Jin Oh, Yeoung Geol Park, Kyung Chul Yoon
Department of Ophthalmology, Chonnam National University Medical School Gwangju, Korea.
검열반과 익상편 환자에서 눈물막과 안구표면의 변화
Department of Ophthalmology, Chonnam National University Medical School Gwangju, Korea
Correspondence:  Han Jin Oh, M.D.
This study was performed to evaluate the parameters of tear function and ocular surface in patients with pinguecula and pterygium. METHODS: The corneal sensitivity test (CST), tear break-up time (BUT), basal tear secretion test, fluorescein staining, rose bengal staining, tear clearance test, and conjunctival impression cytology were evaluated in patients with unilateral pinguecula and pterygium. The results were also evaluated according to the severity of pterygium. RESULTS In patients with pinguecula, BUT (P=0.03) and goblet cell density (P<0.01) were decreased, while the rose bengal staining score (P=0.01) was increased significantly. In patients with pterygium, CST (P=0.01), BUT (P<0.01), and goblet cell density (P<0.01) decreased, and the fluorescein staining score (P<0.01), rose bengal staining score (P<0.01) and grade of conjunctival metaplasia (P<0.01) increased significantly. In comparison with mild pterygium, moderate pterygium demonstrated decreased CST (P=0.01) and BUT (P=0.01), and an increased rose bengal staining score (P=0.04). CONCLUSIONS: The tear films and ocular surface changes in patients with pinguecula and pterygium are worse than in control group. Also, there is close correlation between the severity of pterygium and dry eye condition.
Key Words: Ocular surface;Pinguecula;Pterygium;Tear film

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