Combined Phototherapeutic Keratectomy and Amniotic Membrane Transplantation in the Treatment of Salzmann's Nodular Degeneration. |
In Young Jeong, Kyung Chul Yoon |
Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Korea. kcyoon@chonnam.ac.kr |
치료레이저각막절제술과 양막이식술의 동시 시행에 의한 잘쯔만결절변성의 치료효과 |
정인영,윤경철 |
Department of Ophthalmology, Chonnam National University Medical School & Hospital, Gwangju, Korea |
Correspondence:
In Young Jeong, M.D. |
|
Abstract |
PURPOSE To evaluate the therapeutic effects of excimer laser phototherapeutic keratectomy (PTK) combined with amniotic membrane transplantation (AMT) in patients with symptomatic Salzmann's nodular degeneration. METHODS: Eight eyes of 8 patients who underwent PTK and AMT for Salzmann's nodular degeneration with a minimum follow-up period of 12 months were included. Changes of vision, refraction and symptom, postoperative corneal status, recurrence, and postoperative complication were analyzed retrospectively. RESULTS: Postoperative visual acuity improved more than 2 lines in 6 eyes (75.0%) and was unchanged in 2 eyes (25.0%). The mean myopic shift was 0.83 D. Symptoms improved and cosmetic results were good in all patients. Four patients (50.0) had complete resolution of symptoms. No recurrence of the nodule or postoperative complication was detected during a mean follow-up of 19.12+/-8.20 months. CONCLUSIONS: Combined PTK and AMT is a effective and safe method for treating and preventing the recurrence of symptomatic Salzmann's nodular degeneration. |
Key Words:
Amniotic membrane transplantation;Excimer laser;Phototherapeutic keratectomy;Salzmann's nodular degeneration |