Journal of the Korean Ophthalmological Society 2006;47(7):1080-1086.
Published online July 31, 2006.
Fine-Needle Aspiration Biopsy of Intraocular Tumors.
Jong Hyun Lee, Woo Ick Yang, Sung Chul Lee
1Department of Ophthalmology, Ilsan Paik Hospital, College of Medicine, Inje University, Gyeonggi-do, Korea. sunglee@yumc.yonsei.ac.kr
2Department of Pathology, Yonsei Yonsei University College of Medicine, Seoul, Korea.
3Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
세침 흡인 생검을 이용한 안내 종양의 진단
이종현1,양우익2,이성철3
Department of Ophthalmology, Ilsan Paik Hospital, College of Medicine, Inje University1, Gyeonggi-do, Korea Department of Pathology, Yonsei Yonsei University College of Medicine2, Seoul, Korea Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine3, Seoul, Korea
Correspondence:  Jong Hyun Lee, M.D.1
Abstract
PURPOSE
To evaluate the efficacy and safety of fine-needle aspiration biopsy in the diagnosis of suspected intraocular malignancy and simulating conditions. METHODS: We performed a retrospective study of the medical records of patients who underwent diagnostic pars plana transvitreal biopsy. RESULTS: A total of 12 biopsies were performed in 11 eyes of 11 patients with intraocular tumor and the final diagnosis was confirmed by cytologic examination in 10 eyes. There was insufficient amount of material for cytologic examination in one case. In another case, biopsy was repeated to obtain the final result due to false negative result of the first biopsy. Localized intraocular hemorrhage was found to be the most common complication, but resolved spontaneously in most cases. Retinal detachment and tumor recurrence were not observed. CONCLUSIONS: Transvitreal fine-needle aspiration biopsy is an accurate diagnostic procedure in the evaluation of intraocular tumors difficult to diagnose with other non-invasive diagnostic technique and it can be performed safely with minimal complication.
Key Words: Fine-needle aspiration biopsy;Intraocular tumor;Malignant melanoma


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