Journal of the Korean Ophthalmological Society 2006;47(10):1673-1677.
Published online October 31, 2006.
Benign Mixed Tumor Arising from an Accessory Lacrimal Gland in the Inferior Palpebral Conjunctiva.
Nam Ju Kim, Ho Kyung Choung, Sang In Khwarg
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@snu.ac.kr
2Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggido, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.
아래눈꺼풀결막의 덧눈물샘에서 발생한 양성혼합종 1예
김남주1,2,정호경1,3,곽상인1
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital2, Gyeonggido, Korea Department of Ophthalmology, Seoul National University Boramae Hospital3, Seoul, Korea
Correspondence:  Nam Ju Kim, M.D.1,2
Abstract
PURPOSE
Benign mixed tumor of the accessory lacrimal gland is a very rare neoplasm, with only one case with presumed origin of Wolfring's gland in domestic literature. We report our experience with a case of a nodular lesion of the lateral lower eyelid which is completely excised and histologically diagnosed as benign mixed tumor from Krause's gland. METHODS: A 68 year-old woman presented with 1 cm-sized subcutaneous mass in right lateral lower eyelid. A hard non-tender movable mass was palpated. After 6 months of observation, the mass was excised through subciliary skin incision. RESULTS: The mass was located deep to the subcutaneous tissue, inferior to lower border of tarsal plate, and was adherent to inferior forniceal conjunctiva. Round 1.2 cm-sized yellow-pink mass was completely excised. Histologic examination showed many glandular elements embedded in a myxoid ground substance, and glandular structures were composed of two layers of inner cuboidal and outer polygonal cell. It was diagnosed as benign mixed tumor from accessory lacrimal gland of Krause. CONCLUSIONS: In any case presenting lower eyelid mass lesion, benign mixed tumor of accessory lacrimal gland should be considered as one of the differential diagnosis.
Key Words: Benign mixed tumor;Conjunctiva;Krause


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