Journal of the Korean Ophthalmological Society 2006;47(12):1993-1998.
Published online December 31, 2006.
The Natural Course of Strabismus associated with Thyroid Ophthalmopathy.
Yeon Hee Lee, Jeong Min Hwang, Sei Yeul Oh
1Department of Ophthalmology Chungnam National University College of Medicine, Daejeon, Korea.
2Department of Ophthalmology Seoul National University School of Medicine, Seoul, Korea.
3Department of Ophthalmology Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea. syoh@smc.samsung.co.kr
갑상샘눈병증과 관련된 사시의 자연경과
이연희1,황정민2,오세열3
Department of Ophthalmology Chungnam National University College of Medicine1, Daejeon, Korea Department of Ophthalmology Seoul National University School of Medicine2, Seoul, Korea Department of Ophthalmology Sungkyunkwan University School of Medicine, Samsung Medical Center3, Seoul, Korea
Correspondence:  Yeon Hee Lee, M.D.1
Abstract
PURPOSE
This study investigated the natural course of strabismus associated with thyroid ophthalmopathy. METHODS: A retrospective review was performed on the medical records of 31 patients with strabismus associated with thyroid ophthalmopathy who had been followed up for more than 6 months and had not received surgery. For the purpose of this study, a significant change of deviation angle was defined as more than 10 prism diopters in the primary position. RESULTS: Forty-two percent of patients showed a significant change in deviation angle during the observation period of 23.8+/-17.7 months. The direction of the change was vertical in 32%, horizontal in 3%, and vertical and horizontal in 6% of patients. A significant change of deviation angle developed in 30% of patients within 6 months from the initial ophthalmologic examination, in 24% between 6 and 12 months, and in 13% of patients between 12 and 18 months from the initial examination. CONCLUSIONS: Although the deviation angle of strabismus associated with thyroid ophthalmopathy tended to stabilize with time, it nonetheless was susceptible to change even 12 months after the initial ophthalmologic examination. In addition, a vertical change in the deviation angle was more frequent than a horizontal change.
Key Words: Natural course;Strabismus;Thyroid ophthalmopathy


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