| Expanded Polytetrafluoroethylene as a Wrapping Material for Porous Polyethylene Orbital Implant. |
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Sang Jin Kim, Sang In Khwarg, Ho Kyung Choung |
1Department of ophthalmology, Seoul National University College of Medicine, Korea. hokyung@medimail.co.kr
2Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Korea.
3Department of ophthalmology, Seoul Municipal Boramae Hospital, Seoul, Korea. |
| 다공성 폴리에틸렌 안와 삽입물의 피복 재료로서 신전된 폴리테트라플루오로에틸렌의 이용 |
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김상진1,2,곽상인1,2,정호경1-3 |
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Department of ophthalmology, Seoul National University College of Medicine,1 Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital,2 Department of ophthalmology, Seoul Municipal Boramae Hospital3, Seoul, Korea |
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Correspondence:
Sang Jin Kim, M.D.1,2 |
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| Abstract |
PURPOSE
To investigate the possibility of expanded polytetrafluoroethylene (e-PTFE) as a wrapping material for porous polyethylene orbital implant. METHODS: Two groups of 6 female New Zealand albino rabbits underwent enucleation with placement of a 12 mm porous polyethylene orbital implant wrapped in simple e-PTFE in one group (group 1) and macro-porous e-PTFE in the other group (group 2). Histopathologic sections of the implants obtained at 4, 6, 8 weeks were compared on the extent of fibrovascular ingrowth, percentage of the area of proliferated vessel, and grade of fibrosis between the two groups. RESULTS: There was no implant exposure or severe inflammation in group 1 and 2 during the observation. The extent of fibrovascular ingrowth differs only at 4 weeks. Group 1 showed less fibrovascular ingrowth (until outer 1/3) at anterior half compared with posterior one, but there was no difference between anterior and posterior half in group 2 (until middle 1/3). The percentage of the area of the proliferated vessels was higher in group 2 than group 1 at both anterior and posterior half, and the anterior/posterior ratio of the area of vessels was also higher in group 2 than group 1. The grade of fibrosis was higher in group 2 than group 1 at 4, 6, and 8 weeks. CONCLUSIONS: Macro-porous e-PTFE almost didn't disturb fibrovascular ingrowth into the orbital implant, so macro-porous e-PTFE can be used safely as a wrapping material for porous polyethylene orbital implant. |
| Key Words:
Expanded Polyetetrafluoroethylene;Porous polyethylene orbital implant;Wrapping material |
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