The Results of Cyanoacrylate Glue Application for Corneal Perforation and Impending Perforation. |
Joon Young Lee, Byoung Yeop Kim, Tae Yon Kim |
Department of Ophthalmology, Kim's Eye Hospital, Myong Gok Ophthalmologic Research Institute, Korea. kimtyon@yahoo.co.kr |
각막궤양으로 인한 천공 및 절박천공에서의 조직접착제(Cyanoacrylate Glue)의 치료결과 |
이준영 ( Lee Jun Yeong ) , 김병엽 ( Kim Byeong Yeob ) , 김태연 ( Kim Tae Yeon ) |
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Abstract |
PURPOSE To investigate the effectiveness of cyanoacrylate glue application in cases of corneal perforation or impending perforation due to refractory keratitis. METHODS: Cyanoacrylate glue was applied on 6 cases of fungal keratitis, 3 cases of herpetic keratitis, and 3 cases of bacterial keratitis from July 1998 to June 2002. 2 cases were corneal perforations and 10 were impending perforations. Cyanoacrylate glue was applied on stromal melting area including normal epithelium. When fibrovascular tissue grew beneath the glue sufficiently, glue was removed. When glue was sloughed off spontaneously or fibrovascular tissue was found to be insufficient, glue was reapplied. RESULTS: After average follow up of 25 weeks, the corneal surface was stabilized in 11 eyes except 1 case of fungal keratitis that had broad area of stromal melting(5.4mm). After use of glue, process of stromal melting was found to be discontinued. As fibrovascular tissue grew up beneath the glue, corneal surface became stable. Average diameter of stromal melting area and of glue application area was 4.0mm and 4.4mm respectively. Average duration of glue application was 17 weeks. CONCLUSIONS: Cyanoacrylate glue application appears to be an effective and convenient method in cases of corneal perforations and impending perforations associated with advanced and extensive fungal, bacterial, and herpetic keratitis with active keratolysis. |
Key Words:
Cyanoacrylate glue;Corneal perforation;Impending perforation;Keratolysis |
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