Journal of the Korean Ophthalmological Society 2004;45(3):396-404.
Published online March 1, 2004.
Effect of the Aspheric RGP Lens on Corneal Topography and Endothelial Cell in Keratoconus.
Dong Bin Shin, Nam Su Han, Mee Kum Kim, Jae Lim Lee, Chang Sik Kim
1Department of Ophthalmology, College of medicine, Chungnam National University, Daejon, Korea. opht@unitel.co.kr
2Department of Ophthalmology, College of medicine, Seoul National University Hospital, Seoul, Korea.
원추각막 환자에서 비구면 RGP 렌즈착용이 각막지형도 및 내피세포에 미치는 효과
신동빈 ( Sin Dong Bin ) , 한남수 ( Han Nam Su ) , 김미금 ( Kim Mi Geum ) , 이재림 ( Lee Jae Lim ) , 김창식 ( Kim Chang Sig )
Abstract
PURPOSE
To analyze the effects of the aspheric rigid gas permeable (RGP) lens on the corneal topography and endothelial cells in eyes with keratoconus. METHODS: Sixty five eyes of 35 keratoconic patients who had follow-up of more than 6 months were included in the study. Thirty eyes of 16 patients wore aspheric RGP lens, and the remaining control eyes did not wear any lens. After aspheric RGP lens fitting, visual acuity and manifest refractive error were evaluated, Slit lamp examination and corneal topography were also done. Mean cell area and density of corneal endothelial cell were measured by specular microscopy at first visit and 6 months after lens fitting. RESULTS: After lens fitting, the percentage of best corrected visual acuity of better than 20/25 was 93.3% (28 eyes). The change of astigmatism, the Steepest Simulated keratometry reading, Surface asymmetry index, Surface regularity index, and apical corneal power were significantly increased in the keratoconic cornea in aspheric lens fitting group compared to the control group (p<0.05) There was no significant difference in corneal endothelial cell counts and mean cell areas between the two groups (p>0.05). CONCLUSIONS: Short-term wearing of aspheric RGP lens in keratoconic patients showed no effect on corneal endothelial cells. However, it increased the irregularity and steepening of the keratoconic cornea. It may indicate that mid-peripheral corneal-to-lens relationship may be inappropriate when keratoconus is fitted with aspheric lens.
Key Words: Aspheric RGP lens;Corneal endothelium;Keratoconus;SAI;SRI;Sim-K


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