Journal of the Korean Ophthalmological Society 2004;45(3):413-418.
Published online March 1, 2004.
The Effect of Intravitreal Triamcinolone Acetonide on Cystoid Macular Edema.
Jeong Lee, Jae Hyun Lee
1Department of Ophthalmology, Inje University Sanggye Paik Hospital, Korea.
2Department of Ophthalmology, Inje University Seoul Paik Hospital, Korea. jaehyunn@lycos.co.kr
낭포성 황반부종에 대한 유리체내 Triamcinolone Acetonide 주입의 효과
이정 ( Lee Jeong ) , 이재현 ( Lee Jae Hyeon )
Abstract
PURPOSE
To investigate the use of intravitreal injection of triamcinolone acetonide for the treatment of cystoid macular edema (CME) of various causes. METHODS: Thirty one patients with CME were participated in this study. Six patients were with diabetic retinopathy, seven were with branch retinal vein occlusion, six were with central retinal vein occlusion, seven were with uveitis, and five were with tractional membrane. At first and third month after injection of triamcinolone acetate (4 mg/0.1cc), best corrected visual acuity and thickness of macula by OCT-3000 (Zeiss) were measured. The results were analyzed by paired t-test (SAS 8.0 version). RESULTS: Average best corrected visual acuity was 0.17 0.08, and average macular thickness was 524 +/- 122 micrometer before injection. At first month after injection, the results were 0.33 +/- 0.12 and 309 +/- 150 micrometer. At third month after injection, the results were 0.38 +/- 0.15 and 304 +/- 156 micrometer. Eventhough transient increase of intraocular pressure happened in one eye, there were no complications affecting visual acuity. Injection of triamcinolone acetonide was effective especially in the patients with branch retinal vein occlusion and uveitis. CONCLUSIONS: Intravitreal injection of triamcinolone acetonide for the treatment of CME of various causes showed improvement of visual acuity and anatomic recovery. Study with longer observation and more participants may be necessary for further evaluation.
Key Words: Cystoid macular edema;Intravitreal injection;Triamcinolone acetonide


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