Electroretinogram in Experimental Ocular Siderosis.

Lee, Jae Heung; Youn, Won Shik

Original Article

Journal of the Korean Ophthalmological Society 1968;9(2):7-12.

Electroretinogram in Experimental Ocular Siderosis.

Jae Heung Lee, Won Shik Youn

Department of Ophthalmology, College of Medicine, Seoul National University, SeouI, Korea.

실험적 (實驗的) 안구철침착증의 (眼球鐵沈着症) ( ERG )

이재흥(Jae Heung Lee),윤원식(Won Sik Yoon)

Abstract

Experimental ocular siderosis was induced in fourteen albino rabbits by the insertion of iron fragments through the scleral incision made at equatorial region. ERGs were recorded up to 30 days after the insertion of iron, both in scotopic and photopic conditions. Light stimulus used was electronic photoflash of 2 msec duration. The changes in the scotopic b-wave were classified into 3 types. The first type (4 eyes) showed gradual decrease finally attaining 54.6% of the original amplitude. The second type (3 eyes) showed supernormal b-wave during whole period of study, the increase reached 43.0% after 30 days. In the third type (6 eyes) the b-potential remained almost stationary. The scotopic a-wave changed in a similar way as the b-wave. Sometimes negative (-) type ERGs were recorded, especially during the falling stage of the b-potential. The photopic a- and b-waves changed almost parallel to the scotopic components. By slitlamp biomicroscopy and ophthalmoscopy, fibrous connective tissue proliferated around the iron fragments, never extending deep into the vitreous body. Fundi were well visible except the insertion site. Histological section revealed moderate scar tissue formation around the insertion site of iron, and mild visual cell and ganglion cell destructions.