| Differences in Intraocular Pressure, Corneal Thickness, and Corneal Endothelium Related to Duration in Diabetes. |
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Gi Hong Koo, Seung Youn Jea, Jong Soo Lee, Boo Sup Oum |
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Department of Ophthalmology, Pusan National University College of Medicine, Busan, Korea. jongsool@hyowon.pusan.ac.kr |
| 당뇨병의 유병기간에 따른 안압과 각막의 형태 비교 |
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구기홍 ( Gi Hong Koo ) , 제승연 ( Seung Youn Jea ) , 이종수 ( Jong Soo Lee ) , 엄부섭 ( Boo Sup Oum ) |
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| Abstract |
PURPOSE
This study evaluated the differences of intraocular pressure (IOP), corneal thickness, and corneal endothelial morphology compared with age-matched, healthy control subjects, as well as the correlation according to the duration of diabetes. METHODS: Goldmann applanation tonometry, ultrasound pachymetry, and non-contact specular microscopy were performed in 200 patients with diabetes and 100 control subjects. RESULTS: The diabetic subjects had higher IOP, thicker cornea and less cell density, less hexagonality, and more irregular cell size of corneal endothelium than the controls (P<0.05). Central corneal thickness and coefficient of variation in cell size were higher in diabetes of over 10 years duration than in diabetes of under 10 years duration (P<0.05), while endothelial cell density and percentage of hexagonal cells were lower in the diabetes of over 10 years group (P<0.05). Central corneal thickness was correlated with duration of diabetes but IOP and corneal endothelial morphologic characteristics were not. CONCLUSIONS: Especially, those with a diabetes duration of over 10 years have more corneal morphological abnormalities and a higher IOP than normal subjects. Therefore, any surgical procedures should be performed carefully in the diabetic cornea that is easily damaged by, for example, phacoemulsification. |
| Key Words:
Duration of diabetes;Pachymetry;Specular microscopy |
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