Journal of the Korean Ophthalmological Society 2004;45(9):1427-1437.
Published online September 1, 2004.
Effect of the Spheric Multi-curve Lens on Changes of Corneal Topography and Endothelial Cell in Keratoconus.
Ki Mock Yang, Mee Kum Kim, Jae Lim Lee, Chang Sik Kim
1Department of Ophthalmology, Chungnam National University College of Medicine, Daejon, Korea.
2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
원추각막에서 구면다곡률렌즈 착용이 각막지형도 및 내피세포에 미치는 영향
양기목 ( Ki Mock Yang ) , 김미금 ( Mee Kum Kim ) , 이재림 ( Jae Lim Lee ) , 김창식 ( Chang Sik Kim )
To analyze the effect of the spheric multi-curve lens on the changes of corneal topography and endothelial cells in keratoconic eye. METHODS: Forty-nine eyes of 37 keratoconic patients who had been followed more than 6 months were included in the study. Twenty-six eyes of 19 patients were fitted with spheric multi-curve lens, and the remaining 23 eyes of 18 patients were followed without any lens fitting as control. After spheric multi-curve lens fitting, visual acuity, and slit lamp examination were evaluated. Changes of corneal topography and endothelial cell were evaluated at first visit and 6 months after lens fitting. RESULTS: After lens fitting, 21 eyes (80.8%) showed best corrected visual acuity of better than 20/25. The value of the steepest Sim-K, shape factor (SF), and apical corneal power on corneal topography were significantly decreased in the spheric multi-curve lens fitting group compared to the control group (p<0.05). On the other hand, the value of the flattest Sim-K, and corneal irregularity measure (CIM) were not significantly changed (p>0.05). There were no significant differences in change of corneal endothelial cell density, mean cell area and percentage of hexagonal cell between the two groups (p>0.05). CONCLUSIONS: Short-term wearing of spheric multi-curve lens for 6 months in keratoconic patients showed no effect on progression of keratoconus and cornealendothelial cells.
Key Words: Corneal topography;Endothelial cell;Keratoconus;Spheric multi-curve lens

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