| Relationship between Diabetic Retinopathy and Arteriolosclerosis in Patients with NIDDM (Non-insulin-dependent diabetes mellitus). |
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Won Tae Kim, Ho Kyun Cho, Hyung Bok Park |
1Department of Ophthalmology, Inje University College of Medicine, Koyang-si, Korea. phb@ilsanpaik.ac.kr
2Department of Ophthalmology, ChungAng University, Seoul, Korea. |
| 인슐린 비의존형 당뇨병 환자군에서의 당뇨망막병증과 동맥경화증의 상관관계 |
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김원태 ( Won Tae Kim ) , 조호균 ( Ho Kyun Cho ) , 박형복 ( Hyung Bok Park ) |
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| Abstract |
PURPOSE
To evaluate the correlation between diabetic retinopathy (DR) and arteriolosclerosis in patients with NIDDM (non-insulin-dependent diabetes mellitus), to investigate the risk factors of DR, and to assess the change of the correlation according to the risk factors. METHODS: The study subjects were selected from consecutive routine clinical visits by random sampling from July 2002 to June 2003. The patients were divided into two groups according to the presence of DR, and the patients' charts, fundus examination and blood test were retrospectively reviewed. ETDRS (Early Treatment DR Study) classification for DR and Scheie classification for arteriolosclerosis were used. Statistical analysis was conducted with SPSS program (version 10.0). The confidence interval was set to 95%, and the level of significance was set at p=0.05. RESULTS: DR had a statistically significant correlation with arteriolosclerosis, especially according to duration of diabetes mellitus (p<0.05). Risk factors including diabetes mellitus duration, HgA1c level, and LDL (low-density lipoprotein) cholesterol level showed statistically significant difference (p<0.05). CONCLUSIONS: From the result of analysis, DR has a statistically significant correlation with arteriolosclerosis, especially according to the duration of diabetes mellitus. To prevent vision-threatening complications of DR, the degree of arteriolosclerosis as well as risk factors such as diabetes mellitus duration, serum HgA1c level, and LDL (low-density lipoprotein) cholesterol level should be carefully considered and monitored in the evaluation, progression, and treatment of DR. |
| Key Words:
Arteriolosclerosis;Diabetic retinopathy;NIDDM |
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