Journal of the Korean Ophthalmological Society 2004;45(9):1487-1495.
Published online September 1, 2004.
Intravitreal Triamcinolone Injection for Uveitic Cystoid Macular Edema.
Hun Yang, Jong Hyup Hyun, Sung Chul Lee
The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. sunglee@yumc.yonsei.ac.kr
포도막염에 의한 낭포황반부종에서 유리체내스테로이드주사
양훈 ( Hun Yang ) , 현종협 ( Jong Hyup Hyun ) , 이성철 ( Sung Chul Lee )
Abstract
PURPOSE
To investigate the results of intravitreal injection of triamcinolone acetonide (TA) for the treatment of chronic uveitic cystoid macular edema (CME). METHODS: Six patients, 8 eyes with refractory uveitic CME were included in the study. Four milligrams of TA was injected into the vitreous cavity. The clinical outcome and complication were reviewed, retrospectively. RESULTS: Ten intravitreal injections of TA were performed, and the mean follow-up duration was 10.4 months (6~19 months). Foveal retinal thickness diminished and CME improved anatomically in 7 (88%) eyes. Visual acuity improved by 1.75 lines of the Snellen chart in 6 (75%) eyes, and the time to improvement varied from 1 week to 8 months. Inflammation decreased in all eyes and there was symptomatic improvement in 6 (75%) eyes. CME recurred in 3 (38%) eyes at 4 to 16 weeks and re-treatments were performed in 2 eyes. Intraocular pressure increased in 3 eyes and one eye needed additional filtration surgery. Cataract worsened in one eye. CONCLUSIONS: Intravitreal triamcinolone injection effectively induced anatomic and symptomatic resolution, and decreased inflammation in uveitic CME patients. Nevertheless, the visual improvement was modest, and consideration for recurrence and complication is necessary.
Key Words: Cystoid macular edema;Foveal retinal thickness;Triamcinolone acetonide;Uveitis


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