Diurnal Variation of Macular Thickness in Diabetic Macular Edema.

Oh, In Kyung; Kim, Hyun Seung; Oh, Jaeryung; Huh, Kuhl

Original Article

Journal of the Korean Ophthalmological Society 2005;46(2):279-286.
Published online February 28, 2005.

Diurnal Variation of Macular Thickness in Diabetic Macular Edema.

In Kyung Oh, Hyun Seung Kim, Jaeryung Oh, Kuhl Huh

Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. dumky@unitel.co.kr

당뇨황반부종에서 황반부 망막두께의 하루변화

오인경,김현승,오재령,허걸

Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea

Correspondence: In Kyung Oh, M.D.

Abstract

PURPOSE
To evaluate the diurnal variation of macular thickness in eyes with diabetic macular edema. METHODS: We measured macular thickness using optical coherence tomography in 33 eyes with diabetic macular edema and 33 normal control eyes at 7 am, 11 am, 2 pm, and 5 pm. We investigated the correlation between macular thickness change and several factors such as sex, duration of diabetes mellitus, presence of hypertension, HbA1c, creatinine clearance, blood urea nitrogen, serum creatinine, blood sugar, blood pressure, severity of diabetic retinopathy, and whether PRP was done or not. RESULTS: Retinal thickness in 3.45 mm macular area was the thickest at 7 am and then decreased over the day to be thinnest at 5 pm (p

Key Words: Diurnal variation;Macular thickness;Optical coherence tomography