| Comparative Study on the Epithelial Regeneration of the Corneal Ulceration after Cryocautery and Iodine Cautery. |
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Young Soo Hahn, Haeng Ja Moon, Jong Park Kim |
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Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea. |
| 옥도정기소작법과 (沃度丁幾燒灼法) 동결법후의 (凍結法後) 각막상피재생상태 (角膜上皮再生狀態) |
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김종박(Jong Park Kim),한영수(Young Soo Hahn),문행자(Haeng Ja Moon) |
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| Abstract |
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Recently cryogenic therapy is widely used for the treatment of herpes simplex keratitis. We had experimental studies on the effect of iodine cautery and cryocautery upon the regeneration of corneal ulceration. On 10 adult albino rabbits, one eye was treated by iodine, and the other by cryocautery in area of 0.6cm X 0.6cm. The epithelium in this area was completly removed by cotton applicator. There after, the rate of epithelial regeneration was observed every 12 hours. The results were as follows: (1) The average period of complete epithelial regeneration was 48 hours in animal treated with cryocautery and 78 hours in animals treated with iodine cautery. This difference is statistically highly significant. (2) Corneal opacity was not demonstrated in eyes treated with cryocautery. Six eyes treated with iodine, however, showed various degree of corneal opacities. These results support the view that the healing time in human herpes simplex keratitis is shortened in patients with cryocautery as compared with iodine. |
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