The Analysis of Retinal Nerve Fiber Layer in the Patients with Nonproliferative Diabetic Retinopathy. |
Young Joo Shin, Hak Su Kyoung, Ki Ho Park, Hyeong Gon Yu |
1Department of Ophthalmology1, Seoul National University College of Medicine, Korea. hgonyu@snu.ac.kr 2Artificial Eye Center of Clinical Research Institute, Seoul National University Hospital, Korea. |
비증식성 당뇨망막병증환자에 대한 망막신경섬유층(RNFL)의 분석 |
신영주 ( Sin Yeong Ju ) , 경학수 ( Gyeong Hag Su ) , 박기호 ( Park Gi Ho ) , 유형곤 ( Yu Hyeong Gon ) |
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Abstract |
PURPOSE To investigate the relation between retinal nerve fiber layer (RNFL) defect and grade of diabetic retinopathy in diabetic patients with normal intraocular pressure (IOP). METHODS: The medical records of 260 patients with nonproliferative diabetic retinopathy (NPDR) were reviewed retrospectively. Patients with diseases and congenital anomaly were excluded. According to the results of visual acuity, IOP, slit lamp examination and fluorescein angiography, patients were classified into 3 groups, mild, moderate, severe NPDR. RNFL photography was also performed in all patients. RESULTS: Average age of 260 patients (520 eyes) was 60 year-old, and average IOP was 16.8mmHg. 372 eyes were mild NPDR, 76 were moderate, and 72 were severe. 136 eyes (25.2%) had RNFL defects including wedge-shaped defect (107 eyes; 78.7%) and diffuse atrophy (29 eyes; 21.3%). RNFL defects were observed in patients with mild NPDR (84 eyes), moderate (24 eyes), and severe (28 eyes) and there were a significant correlation between RNFL defect and severity of diabetic retinopathy (p=0.008). CONCLUSIONS: Careful examination and continuous follow-up are necessary in patients with diabetic retinopathy because RNFL defect was common in diabetic patients and increased according to the degree of diabetic retinopathy. |
Key Words:
Diabetic retinopathy;Retinal nerve fiber layer |
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