Human Amniotic Membrane Transplantation for Treatment of Fungal Ulcer.

Oh, Jaeryung; Hong, Jongwook

Original Article

Journal of the Korean Ophthalmological Society 2001;42(3):407-413.
Published online March 1, 2001.

Human Amniotic Membrane Transplantation for Treatment of Fungal Ulcer.

Jaeryung Oh, Jongwook Hong

Department of Ophthalmology, School of Medicine, Korea University, Seoul, Korea.

인간 양막이식을 이용한 진균 각막궤양의 치료

오재령(Jae Ryung Oh),홍종욱(Jong Wook Hung)

Abstract

PURPOSE
Various studies on amniotic membrane transplantation for ocular surface reconstruction have been reported. To investigate the effect of human amniotic membrane transplantation on corneal fungal ulcer, we reviewed the records of four fungal ulcer patients. METHODS: Human amniotic membranes were transplanted to the diseased corneas under topical anesthesia within 12 hours. RESULTS: After the mean observation period of 8.5 months, cornea was stabilized in all eyes. No aggravation or rejection were observed. Secondary penetrating keratoplasty was performed in 2 cases. CONCLUSION: Amniotic membrane transplantation may be effective to promote corneal wound healing in refractory fungal ulcer and considered as a useful treatment prior to corneal transplantation.

Key Words: Amniotic membrane transplantation;Fungal corneal ulcer;PKP