Journal of the Korean Ophthalmological Society 2002;43(1):67-74.
Published online January 1, 2002.
Behcet's Disease in Korean.
Jong Woon Park, Hyoung Jun Koh, Hong Bok Kim
The Institute of Vision Reserch, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea. hjkoh@yumc.yonsei.ac.kr
한국인에서의 베체트병
박종운 ( Jong Woon Park ) , 고형준 ( Hyoung Jun Koh ) , 김홍복 ( Hong Bok Kim )
Abstract
PURPOSE
Behcet's disease is a chronic, recurrent, multisystemic disorder, which visual prognosis is poor. The clinical and epidemiological characteristics of Behcet's disease in Korean were evaluated. METHODS: The clinical records on 3,175 patients with Behcet's disease diagnosed at Behcet's disease clinic in Severance Hospital between November 1983 and December 1999 were reviewed. RESULTS: Among all 3,175 patients, the men/women ratio of Behcet's disease was 1:1.6. The age of disease onset was the highest in the thirties (33.8%). The most frequent major and minor symptom was oral ulcer (97.7%) and arthritis (32.8%) respectively, and the proportion of ocular symptom was 19.3%. The most frequent initial symptom was oral ulcer (77.4%). The ratio of men/women with ocular symptom was 1:0.98. The mean interval between the initial symptom and ocular symptom was 34 months, and the most common ocular symptom was iritis (79.0%). The most frequent systemic drug administered in patients with ocular involvement was colchicines (35%). Visual acuity was worsened in 56% of the eyes followed for over 24 months. CONCLUSIONS: The authors notice the characteristics of Behcet's disease in Korean and suggest that the continuous and nationwide survey is further necessary.
Key Words: Behcet's disease;Clinical and epidemiological characteristics;Nationwide survey


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