Clinical and Histology Findings of Corneal Graft Safety Ring Implanted in Rabbit Cornea.

Lee, Nam Ho; Lee, Dae Kyue; Chung, Young Taek; Ahn, Min

Original Article

Journal of the Korean Ophthalmological Society 2002;43(2):369-374.
Published online February 1, 2002.

Clinical and Histology Findings of Corneal Graft Safety Ring Implanted in Rabbit Cornea.

Nam Ho Lee, Dae Kyue Lee, Young Taek Chung, Min Ahn

Department of Ophthalmology, College of Medicine, Chonbuk National University, Korea. eyegreea@co.kr

가토의 각막에 이식된 각막이식편 안정고리의 임상 및 조직소견

이남호 ( Nam Ho Lee ) , 이대규 ( Dae Kyue Lee ) , 정영택 ( Young Taek Chung ) , 안민 ( Min Ahn )

Abstract

PURPOSE
We developed corneal graft safety ring for improving of penetrating keratoplasty success rate and minimizing the refractive error, and evaluated its stability in the rabbit cornea. METHODS: Following circular corneal incision (depth: 200 microgram, diameter: 7.5 mm) with 7.5 mm Hess-Burg barron vaccum trephine, corneal stroma was dissected toward the corneal center with 6.5 mm diameter. After insertion of the corneal graft safety ring (diameter: 6.0 mm, thickness: 0.15 mm), we examined gross and histologic findings of the rabbit cornea at postoperative 1week, 1month, 3months. RESULTS: The corneal graft safety ring was maintained stable in rabbit cornea for 3months grossly. Histologic finding around corneal graft safety ring showed inflammatory cells and neovascularization which was increased by 1month, and thereafter decreased markedly and maintained stable. CONCLUSIONS: Corneal graft safety ring implantation seemed to be an amenable procedure for improving penetrating keratoplasty outcome.

Key Words: Penetrating keratoplasty;Corneal graft safety ring