Journal of the Korean Ophthalmological Society 2002;43(3):492-497.
Published online March 1, 2002.
The Ocular Manifestations of the Korean Juvenile Rheumatoid Arthritis Children.
Young Joo Shin, Young Suk Yu, Hum Chung, Joong Gon Kim
1Department of Ophthalmology, Seoul National University College of Medicine, Korea. ysyu@snu.ac.kr
2Department of Pediatrics, Seoul National University College of Medicine, Korea.
3Artificial Eye Center of Clinical Research Institute, Seoul National University Hospital, Korea.
한국 소아기 류마티스관절염 환아에서의 안소견
신영주 ( Young Joo Shin ) , 유영석 ( Young Suk Yu ) , 정흠 ( Hum Chung ) , 김중곤 ( Joong Gon Kim )
Abstract
PURPOSE
To investigate the ocular findings, risk factors, and clinical outcomes in juvenile rheumatoid arthritis (JRA) patients. METHODS: JRA patients were classified to polyarticular, pauciarticular and systemic-onset type. We retrospectively analyzed the incidence of uveitis, cataract, elevation of intraocular pressure, and compared them to the type of JRA, gender, the presence of HLA B27 and antinuclear antibody. RESULTS: Acute uveitis in 14 patients (23.7%) of 59 patients manifested 20~37.5% evenly in JRA type except polyarticular rheumatoid factor positive type and systemic-onset type. Chronic uveitis occurred only in 2 pauciarticular type patients. In female, antinuclear antibody positive, HLA B27 positive and pauciarticular type the uveitis was more frequently occured. Cataract was occured in 7 patients (11 eyes, 10.2%), preceded by uveitis in 3 patients (3 eyes) and no history of uveitis in the others (8 eyes). The cataract surgery was performed in 3 patients (4 eyes) due to visual disturbance and then corrected visual acuities were more than 0.7 except one eye with band keratopathy. CONCLUSIONS: This study suggests that the ocular examinations are regularly required in cases of female, the presence of antinuclear antibody and pauciarticular type of JRA patients. Cataract surgery combined with posterior chamber intraocular lens implantation can be done with a good visual results in cases of poor vision.
Key Words: Juvenile rheumatoid arthritis;Uveitis;Cataract;Female;ANA;HLA B27


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